FOXO transcription factors at the interface between longevity and tumor suppression
A wide range of human diseases, including cancer, has a striking age-dependent onset.
However, the molecular mechanisms that connect aging and cancer are just beginning to be …
However, the molecular mechanisms that connect aging and cancer are just beginning to be …
Cancer genetics and genomics of human FOX family genes
M Katoh, M Igarashi, H Fukuda, H Nakagama, M Katoh - Cancer letters, 2013 - Elsevier
Forkhead-box (FOX) family proteins, involved in cell growth and differentiation as well as
embryogenesis and longevity, are DNA-binding proteins regulating transcription and DNA …
embryogenesis and longevity, are DNA-binding proteins regulating transcription and DNA …
Polycomb complexes repress developmental regulators in murine embryonic stem cells
The mechanisms by which embryonic stem (ES) cells self-renew while maintaining the
ability to differentiate into virtually all adult cell types are not well understood. Polycomb …
ability to differentiate into virtually all adult cell types are not well understood. Polycomb …
Control of developmental regulators by Polycomb in human embryonic stem cells
Polycomb group proteins are essential for early development in metazoans, but their
contributions to human development are not well understood. We have mapped the …
contributions to human development are not well understood. We have mapped the …
Molecular subtyping of triple‐negative breast cancers by immunohistochemistry: molecular basis and clinical relevance
S Zhao, D Ma, Y Xiao, XM Li, JL Ma, H Zhang… - The …, 2020 - academic.oup.com
Background Molecular subtyping of triple‐negative breast cancers (TNBCs) via gene
expression profiling is essential for understanding the molecular essence of this …
expression profiling is essential for understanding the molecular essence of this …
Long-range control of gene expression: emerging mechanisms and disruption in disease
DA Kleinjan, V Van Heyningen - The American Journal of Human Genetics, 2005 - cell.com
Transcriptional control is a major mechanism for regulating gene expression. The complex
machinery required to effect this control is still emerging from functional and evolutionary …
machinery required to effect this control is still emerging from functional and evolutionary …
Human FOX gene family
M Katoh, M Katoh - International journal of oncology, 2004 - spandidos-publications.com
Human Forkhead-box (FOX) gene family consists of at least 43 members, including FOXA1,
FOXA2, FOXA3, FOXB1, FOXC1, FOXC2, FOXD1, FOXD2, FOXD3, FOXD4, FOXD5 …
FOXA2, FOXA3, FOXB1, FOXC1, FOXC2, FOXD1, FOXD2, FOXD3, FOXD4, FOXD5 …
Forkhead transcription factors: key players in health and disease
Forkhead box (FOX) proteins constitute an evolutionarily conserved family of transcription
factors with a central role not only during development, but also in the adult organism. Thus …
factors with a central role not only during development, but also in the adult organism. Thus …
The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer
W Li, Z Zhang, X Liu, X Cheng, Y Zhang… - The Journal of …, 2017 - Am Soc Clin Investig
The pathophysiological function of the forkhead transcription factor FOXN3 remains to be
explored. Here we report that FOXN3 is a transcriptional repressor that is physically …
explored. Here we report that FOXN3 is a transcriptional repressor that is physically …
Favorable Prognostic Impact of NPM1 Mutations in Older Patients With Cytogenetically Normal De Novo Acute Myeloid Leukemia and Associated Gene- and …
Purpose To analyze the prognostic significance of NPM1 mutations, and the associated
gene-and microRNA-expression signatures in older patients with de novo, cytogenetically …
gene-and microRNA-expression signatures in older patients with de novo, cytogenetically …