Objectives Genome‐wide association studies (GWAS) have become increasingly popular to
identify associations between single nucleotide polymorphisms (SNPs) and phenotypic …

Mammalian genomes are punctuated by DNA sequences containing an atypically high
frequency of CpG sites termed CpG islands (CGIs). CGIs generally lack DNA methylation …

The Ensembl gene annotation system has been used to annotate over 70 different
vertebrate species across a wide range of genome projects. Furthermore, it generates the …

Cell-line misidentification and contamination with microorganisms, such as mycoplasma,
together with instability, both genetic and phenotypic, are among the problems that continue …

EVidenceModeler (EVM) is presented as an automated eukaryotic gene structure annotation
tool that reports eukaryotic gene structures as a weighted consensus of all available …

Motivation: For most research approaches, genome analyses are dependent on the
existence of a high quality genome reference assembly. However, the local accuracy of an …

We present here a draft genome sequence of the red jungle fowl, Gallus gallus. Because the
chicken is a modern descendant of the dinosaurs and the first non-mammalian amniote to …

Deep sequencing technologies such as Illumina, SOLiD, and 454 platforms have become
very powerful tools in discovering and quantifying small RNAs in diverse organisms …

We report here the results of a systematic search for the existence and prevalence of
potential intramolecular G-quadruplex forming sequences in the human genome. We have …

Background DNA copy number variation (CNV) has been recognized as an important
source of genetic variation. Array comparative genomic hybridization (aCGH) is commonly …