[HTML][HTML] Amygdala circuit substrates for stress adaptation and adversity

WH Zhang, JY Zhang, A Holmes, BX Pan - Biological psychiatry, 2021 - Elsevier
Brain systems that promote the maintenance of homeostasis in face of stress have
significant adaptive value. A growing body of work across species demonstrates a critical …

Neural circuits for the adaptive regulation of fear and extinction memory

SL Plas, T Tuna, H Bayer, VAL Juliano… - Frontiers in Behavioral …, 2024 - frontiersin.org
The regulation of fear memories is critical for adaptive behaviors and dysregulation of these
processes is implicated in trauma-and stress-related disorders. Treatments for these …

The role of avoidance in modulating single prolonged stress effects on emotional memory in male and female rats

B Collins, M Biddle, DR Wood, S Boyapati… - Behavioural Brain …, 2023 - Elsevier
The incidence of post traumatic stress disorder (PTSD) is greater in women than men, but
mechanisms via which this difference manifests remain under explored. The single …

BDNF protein and BDNF mRNA expression of the medial prefrontal cortex, amygdala, and hippocampus during situational reminder in the PTSD animal model

SH Chang, YH Yu, A He, CY Ou, BC Shyu… - Behavioural …, 2021 - Wiley Online Library
Whether BDNF protein and BDNF mRNA expression of the medial prefrontal cortex (mPFC;
cingulated cortex area 1 (Cg1), prelimbic cortex (PrL), and infralimbic cortex (IL)), amygdala …

[HTML][HTML] Parental Reflective Functioning correlates to brain activation in response to video-stimuli of mother–child dyads: Links to maternal trauma history and PTSD

DA Moser, F Suardi, AS Rossignol, M Vital… - Psychiatry Research …, 2019 - Elsevier
Abstract Parental Reflective Functioning is a parent's capacity to infer mental states in
herself and her child. Parental Reflective Functioning is linked to the quality of parent-child …

Daily optogenetic stimulation of the left infralimbic cortex reverses extinction impairments in male rats exposed to single prolonged stress

L Canto-de-Souza, PG Demetrovich, S Plas… - Frontiers in behavioral …, 2021 - frontiersin.org
Post-traumatic stress disorder (PTSD) is associated with decreased activity in the prefrontal
cortex. PTSD-like pathophysiology and behaviors have been observed in rodents exposed …

The effects of orexin‐A and orexin receptors on anxiety‐and depression‐related behaviors in a male rat model of post‐traumatic stress disorder

D Han, Y Shi, F Han - Journal of Comparative Neurology, 2022 - Wiley Online Library
Orexin neurons play an important role in stress‐related mental disorders including post‐
traumatic stress disorder (PTSD). Anxiety‐and depression‐related symptoms commonly …

A prolonged stress rat model recapitulates some PTSD-like changes in sleep and neuronal connectivity

Y Lo, PL Yi, YT Hsiao, TY Lee, FC Chang - Communications Biology, 2023 - nature.com
Chronic post-traumatic stress disorder (PTSD) exhibits psychological abnormalities during
fear memory processing in rodent models. To simulate long-term impaired fear extinction in …

DNA methyltransferase 3A is involved in the sustained effects of chronic stress on synaptic functions and behaviors

J Wei, J Cheng, NJ Waddell, ZJ Wang, X Pang… - Cerebral …, 2021 - academic.oup.com
Emerging evidence suggests that epigenetic mechanisms regulate aberrant gene
transcription in stress-associated mental disorders. However, it remains to be elucidated …

Fear, defense, and emotion: A neuroethological understanding of the negative valence research domain criteria.

MS Fanselow, AN Hoffman - American Psychologist, 2024 - psycnet.apa.org
We describe the close correspondence between predatory imminence continuum theory
(PICT) and the National Institute of Mental Health's Research Domain Criteria (RDoC) for …