Artificial intelligence is an advanced method to identify novel anticancer targets and discover
novel drugs from biology networks because the networks can effectively preserve and …

Advances in the technologies and informatics used to generate and process large biological
data sets (omics data) are promoting a critical shift in the study of biomedical sciences. While …

Global insights into cellular organization and genome function require comprehensive
understanding of the interactome networks that mediate genotype–phenotype relationships …

Just as reference genome sequences revolutionized human genetics, reference maps of
interactome networks will be critical to fully understand genotype-phenotype relationships …

Species interaction networks are shaped by abiotic and biotic factors. Here, as part of the
Tara Oceans project, we studied the photic zone interactome using environmental factors …

Impaired chronic viral and tumor clearance has been attributed to CD8+ T cell exhaustion, a
differentiation state in which T cells have reduced and altered effector function that can be …

INTRODUCTION A disease is rarely a straightforward consequence of an abnormality in a
single gene, but rather reflects the interplay of multiple molecular processes. The …

Cytoscape is open-source software for integration, visualization and analysis of biological
networks. It can be extended through Cytoscape plugins, enabling a broad community of …

As the scientific enterprise has grown in size and diversity, we need empirical evidence on
the research process to test and apply interventions that make it more efficient and its results …

Resources that capture information about signaling pathways from the literature are
essential for the experimental design and analysis of many biological studies. Multiple …