Myasthenia gravis: subgroup classification and therapeutic strategies

NE Gilhus, JJ Verschuuren - The Lancet Neurology, 2015 - thelancet.com
Myasthenia gravis is an autoimmune disease that is characterised by muscle weakness and
fatigue, is B-cell mediated, and is associated with antibodies directed against the …

The immunogenetics of multiple sclerosis: A comprehensive review

JA Hollenbach, JR Oksenberg - Journal of autoimmunity, 2015 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system and
common cause of non-traumatic neurological disability in young adults. The likelihood for an …

[HTML][HTML] Imputing amino acid polymorphisms in human leukocyte antigens

X Jia, B Han, S Onengut-Gumuscu, WM Chen… - PloS one, 2013 - journals.plos.org
DNA sequence variation within human leukocyte antigen (HLA) genes mediate susceptibility
to a wide range of human diseases. The complex genetic structure of the major …

[HTML][HTML] Sex bias in lymphocytes: Implications for autoimmune diseases

KC Dodd, M Menon - Frontiers in Immunology, 2022 - frontiersin.org
Autoimmune diseases are characterized by a significant sex dimorphism, with women
showing increased susceptibility to disease. This is, at least in part, due to sex-dependent …

[HTML][HTML] Clinical features, pathogenesis, and treatment of myasthenia gravis: a supplement to the Guidelines of the German Neurological Society

N Melzer, T Ruck, P Fuhr, R Gold, R Hohlfeld… - Journal of …, 2016 - Springer
Myasthenia gravis (MG) is an autoimmune antibody-mediated disorder of neuromuscular
synaptic transmission. The clinical hallmark of MG consists of fluctuating fatigability and …

Myasthenia gravis: a comprehensive review of immune dysregulation and etiological mechanisms

S Berrih-Aknin, R Le Panse - Journal of autoimmunity, 2014 - Elsevier
Autoimmune myasthenia gravis (MG) is characterized by muscle weakness caused by
antibodies directed against proteins of the neuromuscular junction. The main antigenic …

Diagnostic and clinical classification of autoimmune myasthenia gravis

S Berrih-Aknin, M Frenkian-Cuvelier, B Eymard - Journal of autoimmunity, 2014 - Elsevier
Myasthenia gravis is characterized by muscle weakness and abnormal fatigability. It is an
autoimmune disease caused by the presence of antibodies against components of the …

The different roles of the thymus in the pathogenesis of the various myasthenia gravis subtypes

A Marx, F Pfister, B Schalke, G Saruhan-Direskeneli… - Autoimmunity …, 2013 - Elsevier
The thymus plays distinct roles in the pathogenesis of the different Myasthenia gravis (MG)
subtypes. Inflammatory, neoplastic and age-related alterations of the thymus are of pivotal …

[HTML][HTML] Myasthenia gravis-specific aberrant neuromuscular gene expression by medullary thymic epithelial cells in thymoma

Y Yasumizu, N Ohkura, H Murata, M Kinoshita… - Nature …, 2022 - nature.com
Myasthenia gravis (MG) is a neurological disease caused by autoantibodies against
neuromuscular-associated proteins. While MG frequently develops in thymoma patients, the …

[HTML][HTML] Pathogenesis of myasthenia gravis: update on disease types, models, and mechanisms

WD Phillips, A Vincent - F1000Research, 2016 - ncbi.nlm.nih.gov
Myasthenia gravis is an autoimmune disease of the neuromuscular junction (NMJ) caused
by antibodies that attack components of the postsynaptic membrane, impair neuromuscular …