Drug resistance is the most significant causes of cancer chemotherapy failure. Various
mechanisms of drug resistance include tumor heterogeneity, tumor microenvironment …

Ingenious nanomedical researches have ameliorated outcomes in cancer theranostics.
Though limitations like non specific distribution generating low signal to noise ratio in …

Dendrimers are polymers with well‐defined 3D branched structures that are vastly utilized in
various neurotheranostics and biomedical applications, particularly as nanocarrier vectors …

Despite the fact that nanocarriers as drug delivery systems overcome the limitation of
chemotherapy, the leakage of encapsulated drugs during the delivery process to the target …

Background In recent years, the use of ferritins as nano-vehicles for drug delivery is taking
center stage. Compared to other similar nanocarriers, Archaeoglobus fulgidus ferritin is …

Small interfering RNA (siRNA) is a class of nucleic acid-based drugs (NABDs) able to block
gene expression by interaction with mRNA before its translation. Small interfering RNAs …

Triple‐negative breast cancer develops from malignant cells within the interior lining of milk
ducts or, less frequently, in the stromal tissues and accounts for≈ 15% of all breast cancers …

This chapter reviews the different techniques for analyzing the chemical-physical properties,
transfection efficiency, cytotoxicity, and stability of covalent cationic dendrimers (CCDs) and …

This study was aimed to develop and evaluate the TMZ-PAMAM-siRNA [temozolomide-
polyamidoamine dendimer-siRNA] dendriplexes for the effective treatment of glioblastoma …

In part I of this review, the authors showed how poly (amidoamine)(PAMAM)-based
dendrimers can be considered as promising delivering platforms for siRNA therapeutics …