The evolution of SARS-CoV-2

PV Markov, M Ghafari, M Beer, K Lythgoe… - Nature Reviews …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …

[HTML][HTML] SARS-CoV-2 viral load and shedding kinetics

O Puhach, B Meyer, I Eckerle - Nature Reviews Microbiology, 2023 - nature.com
SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …

Community transmission and viral load kinetics of the SARS-CoV-2 delta (B. 1.617. 2) variant in vaccinated and unvaccinated individuals in the UK: a prospective …

A Singanayagam, S Hakki, J Dunning… - The lancet infectious …, 2022 - thelancet.com
Summary Background The SARS-CoV-2 delta (B. 1.617. 2) variant is highly transmissible
and spreading globally, including in populations with high vaccination rates. We aimed to …

Onset and window of SARS-CoV-2 infectiousness and temporal correlation with symptom onset: a prospective, longitudinal, community cohort study

S Hakki, J Zhou, J Jonnerby… - The Lancet …, 2022 - thelancet.com
Background Knowledge of the window of SARS-CoV-2 infectiousness is crucial in
developing policies to curb transmission. Mathematical modelling based on scarce empirical …

Shedding of infectious SARS-CoV-2 despite vaccination

KK Riemersma, LA Haddock III, NA Wilson… - PLoS …, 2022 - journals.plos.org
The SARS-CoV-2 Delta Variant of Concern is highly transmissible and contains mutations
that confer partial immune escape. The emergence of Delta in North America caused the first …

Viral dynamics and duration of PCR positivity of the SARS-CoV-2 Omicron variant

JA Hay, SM Kissler, JR Fauver, C Mack, CG Tai… - MedRxiv, 2022 - medrxiv.org
Abstract Background The Omicron SARS-CoV-2 variant is responsible for a major wave of
COVID-19, with record case counts reflecting high transmissibility and escape from prior …

Swift and extensive Omicron outbreak in China after sudden exit from 'zero-COVID'policy

EE Goldberg, Q Lin, EO Romero-Severson… - Nature …, 2023 - nature.com
In late 2022, China transitioned from a strict 'zero-COVID'policy to rapidly abandoning nearly
all interventions and data reporting. This raised great concern about the presumably-rapid …

Quantifying the relationship between SARS-CoV-2 viral load and infectiousness

A Marc, M Kerioui, F Blanquart, J Bertrand, O Mitja… - Elife, 2021 - elifesciences.org
The relationship between SARS-CoV-2 viral load and infectiousness is poorly known. Using
data from a cohort of cases and high-risk contacts, we reconstructed viral load at the time of …

Viral emissions into the air and environment after SARS-CoV-2 human challenge: a phase 1, open label, first-in-human study

J Zhou, A Singanayagam, N Goonawardane… - The Lancet …, 2023 - thelancet.com
Background Effectively implementing strategies to curb SARS-CoV-2 transmission requires
understanding who is contagious and when. Although viral load on upper respiratory swabs …

Quantifying the impact of immune history and variant on SARS-CoV-2 viral kinetics and infection rebound: A retrospective cohort study

JA Hay, SM Kissler, JR Fauver, C Mack, CG Tai… - Elife, 2022 - elifesciences.org
Background: The combined impact of immunity and SARS-CoV-2 variants on viral kinetics
during infections has been unclear. Methods: We characterized 1,280 infections from the …