The concept of a fuel cell dates back to 1839, from independent studies by Grove and
Schoenbein. 1, 2 Like a battery, a fuel cell is a device for obtaining electrical energy directly …

From Egyptian mummies to the Chanel n° 5 perfume, fatty aldehydes have long been used
and keep impacting our senses in a wide range of foods, beverages and perfumes. Natural …

The design and improvement of enzymes based on physical principles remain challenging.
Here we demonstrate that the principle of electrostatic catalysis can be leveraged to …

The two-volume Encyclopedia of Supramolecular Chemistry offers authoritative, centralized
information on a rapidly expanding interdisciplinary field. User-friendly and high-quality …

The most abundant helix type in proteins is the α-helix, accounting for about 31% of amino
acid secondary structure states, while the 310-helix accounts for about 4%. The π-helix …

Driving the machinery: A biocatalytic redox-neutral cascade for the preparation of terminal
primary amines from primary alcohols at the expense of ammonia has been established in a …

7α-Hydroxysteroid dehydrogenase (7α-HSDH; 1 EC 1.1. 1.159) is an NAD+-dependent
oxidoreductase belonging to the short-chain dehydrogenase/reductase (SDR) 1 family. It …

The coordination number of the catalytic zinc ion in alcohol dehydrogenase has been
studied by integrated ab initio quantum-chemical and molecular mechanics geometry …

We present evidence that the size of an active site side chain may modulate the degree of
hydrogen tunneling in an enzyme-catalyzed reaction. Primary and secondary k H/k T and k …

A computational comparison of 102 high‐resolution (≤ 1.90 Å) enzyme‐dinucleotide (NAD,
NADP, FAD) complexes was performed to investigate the role of solvent in dinucleotide …