NTPDase and 5'‐nucleotidase activities in physiological and disease conditions: New perspectives for human health
Extracellular nucleotides and nucleosides act as signaling molecules involved in a wide
spectrum of biological effects. Their levels are controlled by a complex cell surface‐located …
spectrum of biological effects. Their levels are controlled by a complex cell surface‐located …
Platelets in renal disease
D Gomchok, RL Ge, T Wuren - International Journal of Molecular …, 2023 - mdpi.com
Kidney disease is a major global health concern, affecting millions of people. Nephrologists
have shown interest in platelets because of coagulation disorders caused by renal diseases …
have shown interest in platelets because of coagulation disorders caused by renal diseases …
High levels of extracellular ATP lead to different inflammatory responses in COVID-19 patients according to the severity
GB da Silva, D Manica, AP da Silva… - Journal of Molecular …, 2022 - Springer
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
significantly impacted the world and has driven many researchers into the pathophysiology …
significantly impacted the world and has driven many researchers into the pathophysiology …
Characterization of NTPDase (NTPDase1; ecto-apyrase; ecto-diphosphohydrolase; CD39; EC 3.6. 1.5) activity in human lymphocytes
DBR Leal, CA Streher, TN Neu, FP Bittencourt… - … et Biophysica Acta (BBA …, 2005 - Elsevier
Human lymphocytes contain NTPDase (NTPDase-1; ecto-apyrase; ecto-
diphosphohydrolase; CD39; EC 3.6. 1.5), a cation-dependent enzyme that hydrolyzes ATP …
diphosphohydrolase; CD39; EC 3.6. 1.5), a cation-dependent enzyme that hydrolyzes ATP …
Phytochemical and biological characterization of aqueous extract of Vassobia breviflora on proliferation and viability of melanoma cells: involvement of purinergic …
AR Viana, NB Bottari, VR Oviedo, D Santos… - Journal of Toxicology …, 2023 - Taylor & Francis
Vassobia breviflora belongs to the Solanaceae family, possessing biological activity against
tumor cells and is a promising alternative for therapy. The aim of this investigation was to …
tumor cells and is a promising alternative for therapy. The aim of this investigation was to …
Rutin and curcumin reduce inflammation, triglyceride levels and ADA activity in serum and immune cells in a model of hyperlipidemia
AG Manzoni, DF Passos, JLG da Silva… - Blood Cells, Molecules …, 2019 - Elsevier
Hyperlipidemia is associated with endothelial dysfunction and inflammatory disorders.
Adenosine and adenosine deaminase (ADA) modulate immune responses and lipid …
Adenosine and adenosine deaminase (ADA) modulate immune responses and lipid …
NTPDase and 5′-nucleotidase activities in rats with alloxan-induced diabetes
GIL Lunkes, DS Lunkes, VM Morsch… - Diabetes research and …, 2004 - Elsevier
Diabetes is associated with a hypercoagulable state. In this study, we investigated the
potential effects of alloxan-induced diabetes on the activities of the enzymes NTPDase (EC …
potential effects of alloxan-induced diabetes on the activities of the enzymes NTPDase (EC …
Diphenyl diselenide reduces temporarily hyperglycemia: possible relationship with oxidative stress
NBV Barbosa, JBT Rocha, DC Wondracek… - Chemico-biological …, 2006 - Elsevier
This study was designed to determine the effect of diphenyl diselenide and ebselen,
synthetic organoselenium compounds with antioxidant properties, in diabetic rats. Diabetes …
synthetic organoselenium compounds with antioxidant properties, in diabetic rats. Diabetes …
Effects of resveratrol on nucleotide degrading enzymes in streptozotocin-induced diabetic rats
R Schmatz, MRC Schetinger, RM Spanevello… - Life Sciences, 2009 - Elsevier
AIMS: Diabetes mellitus is associated with platelet alterations that may contribute to the
development of cardiovascular complications. The present study investigates the effects of …
development of cardiovascular complications. The present study investigates the effects of …
Adenosine receptors and diabetes: focus on the A2B adenosine receptor subtype
Over the last two decades, diabetes mellitus has become one of the most challenging health
problems worldwide. Diabetes mellitus, classified as type I and II, is a pathology concerning …
problems worldwide. Diabetes mellitus, classified as type I and II, is a pathology concerning …