Asthma is a frequent disease, mainly characterized by airway inflammation, in which drug
therapy is crucial in its management. The potential of pharmacogenomics testing in asthma …

Asthma is a chronic respiratory disease affecting approximately 300 million people
worldwide. 1 In the United States, an estimated 43.3 million people, including 9.3 million …

BACKGROUND: Asthma is the most prevalent chronic disease in the pediatric age group.
The disease affects different aspects of the children's lives, such as physical, emotional …

Introduction Asthma is a heterogeneous, multifactorial disease with multiple genetic and
environmental risk factors playing a role in pathogenesis and therapeutic response …

There is a large interindividual variability in response to ICSs in asthma. About 70% of the
variance in ICS response is likely due at least partially to genetically determined …

Background The FCER2 gene, via encoding of the CD23 receptor, plays an important role in
the regulation of IgE responses. A genetic variant of the FCER2 gene (T2206C) was …

Abstract Introduction Beta‐2‐adrenergic receptor (ADRB2) is present in the cells of the
respiratory tract, including bronchial smooth muscle cells and bronchial epithelium, and is a …

Abstract What Is Known and Objective Patients with optic neuritis (ON) have significant
individual differences in their response to high‐dose intravenous methylprednisolone …

Background Asthma is characterized by chronic airway inflammation, and inhaled
corticosteroids (ICSs) have been recommended as first-line treatment. However, response to …

Inhaled corticosteroids (ICS) are the most common asthma controller medication. An
important contribution of genetic factors in ICS response has been evidenced. Here, we …