Contemporary diagnosis and management of patients with myocardial infarction in the absence of obstructive coronary artery disease: a scientific statement from the …

JE Tamis-Holland, H Jneid, HR Reynolds, S Agewall… - Circulation, 2019 - Am Heart Assoc
Myocardial infarction in the absence of obstructive coronary artery disease is found in≈ 5%
to 6% of all patients with acute infarction who are referred for coronary angiography. There …

Dysfunctional vascular endothelium as a driver of atherosclerosis: emerging insights into pathogenesis and treatment

SR Botts, JE Fish, KL Howe - Frontiers in pharmacology, 2021 - frontiersin.org
Atherosclerosis, the chronic accumulation of cholesterol-rich plaque within arteries, is
associated with a broad spectrum of cardiovascular diseases including myocardial …

Expert recommendations on the assessment of wall shear stress in human coronary arteries: existing methodologies, technical considerations, and clinical …

F Gijsen, Y Katagiri, P Barlis, C Bourantas… - European heart …, 2019 - academic.oup.com
Expert recommendations on the assessment of wall shear stress in human coronary arteries:
existing methodologies, technical considerations, and clinical applications | European Heart …

Effective anti-thrombotic therapy without stenting: intravascular optical coherence tomography-based management in plaque erosion (the EROSION study)

H Jia, J Dai, J Hou, L Xing, L Ma, H Liu… - European Heart …, 2017 - academic.oup.com
Aims Plaque erosion, compared with plaque rupture, has distinctly different underlying
pathology and therefore may merit tailored therapy. In this study, we aimed to assess …

Sex differences in cardiovascular disease–impact on care and outcomes

KH Humphries, M Izadnegahdar, T Sedlak… - Frontiers in …, 2017 - Elsevier
Globally, cardiovascular disease (CVD) is the number one killer of women; one third of
female deaths are due to ischemic heart disease and stroke (WHO, 2013). Historically …

Plaque erosion: a new in vivo diagnosis and a potential major shift in the management of patients with acute coronary syndromes

RA Partida, P Libby, F Crea, IK Jang - European heart journal, 2018 - academic.oup.com
Pathology and in vivo imaging studies have identified superficial plaque erosion as a
frequent and important mechanism underlying acute coronary syndromes (ACS). In contrast …

Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap …

DM Leistner, N Kränkel, D Meteva… - European Heart …, 2020 - academic.oup.com
Aims Acute coronary syndromes with intact fibrous cap (IFC-ACS), ie caused by coronary
plaque erosion, account for approximately one-third of ACS. However, the underlying …

Sex differences in acute coronary syndromes: a global perspective

FA Cader, S Banerjee, M Gulati - Journal of Cardiovascular Development …, 2022 - mdpi.com
Despite increasing evidence and improvements in the care of acute coronary syndromes
(ACS), sex disparities in presentation, comorbidities, access to care and invasive therapies …

Pathophysiology of atherothrombosis: Mechanisms of thrombus formation on disrupted atherosclerotic plaques

Y Asada, A Yamashita, Y Sato… - Pathology …, 2020 - Wiley Online Library
Atherothrombosis is a leading cause of cardiovascular mortality and morbidity worldwide.
The underlying mechanisms of atherothrombosis comprise plaque disruption and …

Nanoparticle-aided characterization of arterial endothelial architecture during atherosclerosis progression and metabolic therapy

TJ Beldman, TS Malinova, E Desclos, AE Grootemaat… - ACS …, 2019 - ACS Publications
Atherosclerosis is associated with a compromised endothelial barrier, facilitating the
accumulation of immune cells and macromolecules in atherosclerotic lesions. In this study …