Astrocyte-derived extracellular vesicles: Neuroreparative properties and role in the pathogenesis of neurodegenerative disorders
Extracellular vesicles (EVs) released by neural cells play an essential role in brain
homeostasis and the crosstalk between neural cells and the periphery. EVs are diverse …
homeostasis and the crosstalk between neural cells and the periphery. EVs are diverse …
Role of the immune system in HIV-associated neuroinflammation and neurocognitive implications
S Hong, WA Banks - Brain, behavior, and immunity, 2015 - Elsevier
Individuals living with HIV who are optimally treated with combination antiretroviral therapy
(cART) can now lead an extended life. In spite of this remarkable survival benefit from viral …
(cART) can now lead an extended life. In spite of this remarkable survival benefit from viral …
Primary care guidance for persons with human immunodeficiency virus: 2020 update by the HIV Medicine Association of the Infectious Diseases Society of America
MA Thompson, MA Horberg, AL Agwu… - Clinical infectious …, 2021 - academic.oup.com
Advances in antiretroviral therapy (ART) have made it possible for persons with human
immunodeficiency virus (HIV) to live a near expected life span, without progressing to AIDS …
immunodeficiency virus (HIV) to live a near expected life span, without progressing to AIDS …
Global prevalence and burden of HIV-associated neurocognitive disorder: a meta-analysis
Objective To characterize the prevalence and burden of HIV-associated neurocognitive
disorder (HAND) and assess associated factors in the global population with HIV. Methods …
disorder (HAND) and assess associated factors in the global population with HIV. Methods …
Time to test antibacterial therapy in Alzheimer's disease
Alzheimer's disease is associated with cerebral accumulation of amyloid-β peptide and
hyperphosphorylated tau. In the past 28 years, huge efforts have been made in attempting to …
hyperphosphorylated tau. In the past 28 years, huge efforts have been made in attempting to …
Exosomes as mediators of neuroinflammation
A Gupta, L Pulliam - Journal of neuroinflammation, 2014 - Springer
Exosomes are membrane-bound nanovesicles that are shed by cells of various lineages
under normal as well as pathological conditions. Previously thought to be 'extracellular …
under normal as well as pathological conditions. Previously thought to be 'extracellular …
The viral protein corona directs viral pathogenesis and amyloid aggregation
Artificial nanoparticles accumulate a protein corona layer in biological fluids, which
significantly influences their bioactivity. As nanosized obligate intracellular parasites, viruses …
significantly influences their bioactivity. As nanosized obligate intracellular parasites, viruses …
The versatile role of exosomes in human retroviral infections: from immunopathogenesis to clinical application
Eukaryotic cells produce extracellular vesicles (EVs) mediating intercellular communication.
These vesicles encompass many bio-molecules such as proteins, nucleic acids, and lipids …
These vesicles encompass many bio-molecules such as proteins, nucleic acids, and lipids …
HIV infection of non-classical cells in the brain
A Wahl, L Al-Harthi - Retrovirology, 2023 - Springer
HIV-associated neurological disorders (HAND) affect up to 50% of people living with HIV
(PLWH), even in the era of combination antiretroviral therapy (cART). HIV-DNA can be …
(PLWH), even in the era of combination antiretroviral therapy (cART). HIV-DNA can be …
GluT4: A central player in hippocampal memory and brain insulin resistance
EC McNay, J Pearson-Leary - Experimental neurology, 2020 - Elsevier
Insulin is now well-established as playing multiple roles within the brain, and specifically as
regulating hippocampal cognitive processes and metabolism. Impairments to insulin …
regulating hippocampal cognitive processes and metabolism. Impairments to insulin …