Recognition and repair of damaged tissue are an integral part of life. The failure of cells and
tissues to appropriately respond to damage can lead to severe dysfunction and disease …

Besides its broad application in research and biotechnology, genome editing (GE) has great
potential for clinical gene therapy, but delivery of GE tools remains a bottleneck. Whereas …

INTRODUCTION Cellular damage caused by wounding triggers signals to alert the
surrounding tissue. As a universal process in all multicellular organisms, these signals …

Collective cell migration is a highly complex process in which groups of cells move together.
A fundamental question is how cell ensembles can migrate efficiently. In some cases, the …

The presence of a wound triggers surrounding cells to initiate repair mechanisms, but it is
not clear how cells initially detect wounds. In epithelial cells, the earliest known wound …

Plasma membrane forms the barrier between the cytoplasm and the environment. Cells
constantly and selectively transport molecules across their plasma membrane without …

Airway epithelium is the first body surface to contact inhaled irritants and report danger.
Here, we report how epithelial cells recognize and respond to aeroallergen alkaline …

The imaging of neuronal activity using calcium indicators has become a staple of modern
neuroscience. However, without ground truths, there is a real risk of missing a significant …

Piezo1 belongs to mechano‐activatable cation channels serving as biological force sensors.
However, the molecular events downstream of Piezo1 activation remain unclear. In this …

Tissue repair is a complex process that requires effective communication and coordination
between cells across multiple tissues and organ systems. Two of the initial intracellular …