Diversity and complexity of cell death: a historical review

W Park, S Wei, BS Kim, B Kim, SJ Bae… - … & molecular medicine, 2023 - nature.com
Death is the inevitable fate of all living organisms, whether at the individual or cellular level.
For a long time, cell death was believed to be an undesirable but unavoidable final outcome …

[HTML][HTML] Multiple cell death modalities and their key features

GE Yan, M Elbadawi, T Efferth - World …, 2020 - … .spandidos-publications.com
Cell death, as a final cellular decision which is reached following complex communications,
represents a critical process with which to maintain organismic homeostasis. Different …

Oxidative cell death in cancer: mechanisms and therapeutic opportunities

X An, W Yu, J Liu, D Tang, L Yang, X Chen - Cell Death & Disease, 2024 - nature.com
Reactive oxygen species (ROS) are highly reactive oxygen-containing molecules generated
as natural byproducts during cellular processes, including metabolism. Under normal …

[HTML][HTML] Cytoplasmic vacuolization in cell death and survival

AV Shubin, IV Demidyuk, AA Komissarov, LM Rafieva… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Cytoplasmic vacuolization (also called cytoplasmic vacuolation) is a well-known
morphological phenomenon observed in mammalian cells after exposure to bacterial or viral …

The molecular era of the mitochondrial calcium uniporter

KJ Kamer, VK Mootha - Nature reviews Molecular cell biology, 2015 - nature.com
The mitochondrial calcium uniporter is an evolutionarily conserved calcium channel, and its
biophysical properties and relevance to cell death, bioenergetics and signalling have been …

Cell death pathways associated with photodynamic therapy: an update

D Kessel, NL Oleinick - Photochemistry and photobiology, 2018 - Wiley Online Library
Photodynamic therapy (PDT) has the potential to make a significant impact on cancer
treatment. PDT can sensitize malignant tissues to light, leading to a highly selective effect if …

Celastrol: a spectrum of treatment opportunities in chronic diseases

R Cascão, JE Fonseca, LF Moita - Frontiers in medicine, 2017 - frontiersin.org
The identification of new bioactive compounds derived from medicinal plants with significant
therapeutic properties has attracted considerable interest in recent years. Such is the case of …

The emerging role of paraptosis in tumor cell biology: Perspectives for cancer prevention and therapy with natural compounds

F Fontana, M Raimondi, M Marzagalli… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Standard anti-cancer therapies promote tumor growth suppression mainly via induction of
apoptosis. However, in most cases cancer cells acquire the ability to escape apoptotic cell …

In vitro anticancer activity and in vivo biodistribution of rhenium (I) tricarbonyl aqua complexes

KM Knopf, BL Murphy, SN MacMillan… - Journal of the …, 2017 - ACS Publications
Seven rhenium (I) complexes of the general formula fac-[Re (CO) 3 (NN)(OH2)]+ where NN=
2, 2′-bipyridine (8), 4, 4′-dimethyl-2, 2′-bipyridine (9), 4, 4′-dimethoxy-2, 2′-bipyridine …

Paraptosis: a unique cell death mode for targeting cancer

S Hanson, A Dharan, J PV, S Pal, BG Nair… - Frontiers in …, 2023 - frontiersin.org
Programmed cell death (PCD) is the universal process that maintains cellular homeostasis
and regulates all living systems' development, health and disease. Out of all, apoptosis is …