As a family of cationic host defense peptides, defensins are mainly synthesized by Paneth
cells, neutrophils, and epithelial cells, contributing to host defense. Their biological functions …

Background Gut microbiota is considered as a major regulator of metabolic disease. This
reconciles the notion of metabolic inflammation and the epidemic development of the …

Objectives To evaluate the expression of proteins related to activation of the NLRP3
inflammasome in patients with chronic periodontitis (CP) and type 2 diabetes mellitus (T2D) …

The nature and structural composition of antimicrobial peptides are derived from their innate
immune response and they are active against various bacteria, fungi and other …

In the pathogenesis of periodontitis, an infection-induced inflammatory disease of the tooth-
supporting tissues, there is a complex interaction between the subgingival microbiota and …

The purpose of this systematic review was to establish if patients suffering from periodontal
diseases present differences in the expression or production of cationic antimicrobial …

Antimicrobial peptides (AMPs) play a critical role in controlling innate and acquired immune
responses. Local dysregulation of AMP is implicated in the pathogenesis of periodontal …

Aim To profile gingival tissue levels of human beta‐defensin (hBD)‐2 and hBD‐3 in relation
to gingival inflammation, Th17‐related cytokine concentrations, Porphyromonas gingivalis …

Objective: Type 2 diabetes mellitus (T2DM) is a well-defined risk factor of periodontitis and it
can affect expression of human beta-defensins (hBDs) and cathelicidin (LL-37) as well. The …

ABSTRACT Group B Streptococcus (GBS) causes frequent urinary tract infection (UTI) in
susceptible populations, including individuals with type 2 diabetes and pregnant women; …