The peripheral nervous system may be involved at any stage in the course of
lymphoproliferative diseases. The different underlying mechanisms include neurotoxicity …

Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are
characterized by a progressive accumulation of leukemic cells in the peripheral blood, bone …

Background Chronic lymphocytic leukaemia (CLL) is the most common cancer of the
lymphatic system in Western countries. Several clinical and biological factors for CLL have …

Complex karyotype (CK) at chronic lymphocytic leukemia (CLL) diagnosis is a negative
biomarker of adverse outcome. Since the impact of CK and its subtypes, namely type-2 CK …

The bone marrow microenvironment promotes proliferation and drug resistance in chronic
lymphocytic leukemia (CLL). Although ibrutinib is active in CLL, it is rarely able to clear …

Simple Summary The peripheral nervous systems may be involved by several
hematological diseases ranging from preneoplastic diseases to overt malignancies or …

Background Complex karyotype (CK) is a heterogeneous category with a negative impact in
chronic lymphocytic leukaemia (CLL). Our group has recently reported that CK patients with …

Background Most important markers in chronic lymphocytic leukemia (CLL) are TP53
abnormalities, including mutations and deletions, and the mutational status of …

The article discusses the Richter syndrome (RS) which is the transformation of chronic
lymphocytic leukaemia (CLL) into an aggressive lymphoma like the diffuse large B cell …

Simple Summary In this study, we present a retrospective analysis of a large cohort of CLL
patients with a particular focus on those with a borderline immunoglobulin heavy variable …