Abstract The original Human Connectome Project yielded a rich data set on structural and
functional connectivity in a large sample of healthy young adults using improved methods of …

The availability of neuroimaging technology has spurred a marked increase in the human
cognitive neuroscience literature, including the study of cognitive ageing. Although there is a …

Gene expression studies suggest that aging of the human brain is determined by a complex
interplay of molecular events, although both its region-and cell-type-specific consequences …

The structure of the brain is constantly changing from birth throughout the lifetime, meaning
that normal aging, free from dementia, is associated with structural brain changes. This …

There are declines with age in speed of processing, working memory, inhibitory function,
and long-term memory, as well as decreases in brain structure size and white matter …

Cerebral white matter (WM) degeneration occurs with increasing age and is associated with
declining cognitive function. Research has shown that cardiorespiratory fitness and exercise …

Physical activity has been shown to improve cognitive functioning. Research has largely
focused on cognitive facilitation by cardiovascular exercise in older adults. Only few studies …

As we grow older, we may grow wiser, but we can also experience memory loss and
cognitive slowing that can interfere with our daily routines. The cognitive neuroscience of …

Brain aging research relies mostly on cross-sectional studies, which infer true changes from
age differences. We present longitudinal measures of five-year change in the regional brain …

Brain anatomical networks are sparse, complex, and have economical small-world
properties. We investigated the efficiency and cost of human brain functional networks …