Drug delivery to central nervous system (CNS) diseases is very challenging since the
presence of the innate blood–brain barrier (BBB) and the blood-cerebrospinal fluid barrier …

Inflammation, a common feature of many diseases, is an essential immune response that
enables survival and maintains tissue homeostasis. However, in some conditions, the …

Ischemic stroke is a cerebrovascular disease normally caused by interrupted blood supply to
the brain. Ischemia would initiate the cascade reaction consisted of multiple biochemical …

The blood-brain barrier (BBB) is a vital component of the neurovascular unit (NVU)
containing tight junctional (TJ) proteins and different ion and nutrient transporters which …

Alzheimer's disease (AD) is closely associated with neuroinflammation development in the
brain. Co-delivery of metformin (MET) with phosphatidylserine liposomes neuroprotectant …

Neuroinflammation, an inflammatory response within the central nervous system (CNS), is a
main hallmark of common neurodegenerative diseases, including Alzheimer's disease (AD) …

Ischemic stroke remains the leading cause of death and disability, while the main
mechanisms of dominant neurological damage in stroke contain excitotoxicity, oxidative …

Cardiovascular diseases (CVD) including acute myocardial infarction (AMI) rank first in
worldwide mortality and according to the World Health Organization (WHO), they will stay at …

Stroke is one of the leading causes of mortality and morbidity worldwide. Due to its poor
prognosis, there is a major negative impact on the patients and their family's life quality …

Owing to its intricate pathophysiology, cerebral stroke is a serious medical condition caused
by interruption or obstruction of blood supply (blockage of vasculature) to the brain tissues …