Recovery and purification process development for monoclonal antibody production

HF Liu, J Ma, C Winter, R Bayer - MAbs, 2010 - Taylor & Francis
Hundreds of therapeutic monoclonal antibodies (mAbs) are currently in development, and
many companies have multiple antibodies in their pipelines. Current methodology used in …

Bioprocess membrane technology

R van Reis, A Zydney - Journal of Membrane Science, 2007 - Elsevier
Membrane processes play a critical role in the purification of biotechnology products. Early
membrane systems were adopted from technology originally developed for other industrial …

[图书][B] Microfiltration and ultrafiltration: principles and applications

LJ Zeman, AL Zydney - 2017 - taylorfrancis.com
Integrates knowledge on microfiltration and ultrification, membrane chemistry, and
characterization methods with the engineering and economic aspects of device …

[图书][B] Handbook of membrane separations: chemical, pharmaceutical, food, and biotechnological applications

AK Pabby, SSH Rizvi, AMS Requena - 2008 - taylorfrancis.com
The Handbook of Membrane Separations: Chemical, Pharmaceutical, and Biotechnological
Applications provides detailed information on membrane separation technologies as they …

Future of antibody purification

D Low, R O'Leary, NS Pujar - Journal of Chromatography B, 2007 - Elsevier
Antibody purification seems to be safely ensconced in a platform, now well-established by
way of multiple commercialized antibody processes. However, natural evolution compels us …

Photo-induced graft polymerization surface modifications for the preparation of hydrophilic and low-proten-adsorbing ultrafiltration membranes

M Ulbricht, H Matuschewski, A Oechel… - Journal of Membrane …, 1996 - Elsevier
Heterogeneous surface modifications of PAN UF membranes with either simultaneous or
sequential UV irradiation-initiated graft polymerizations of monomers from water solutions …

Protein separations using membrane filtration: new opportunities for whey fractionation

AL Zydney - International Dairy Journal, 1998 - Elsevier
There is considerable commercial interest in the preparation of individual whey proteins for
food, nutraceutical, and therapeutic applications. Recent developments in membrane …

Nanofiltration of natural organic matter: pH and ionic strength effects

A Braghetta, FA DiGiano, WP Ball - Journal of environmental …, 1997 - ascelibrary.org
Studies were conducted to examine the effect of solution chemistry, defined here as pH and
ionic strength, on the permeability of negatively charged polymeric nanofiltration …

High performance tangential flow filtration

R Van Reis, S Gadam, LN Frautschy… - Biotechnology and …, 1997 - Wiley Online Library
Conventional tangential flow filtration (TFF) has traditionally been limited to separation of
solutes that differ by about ten‐fold in size. Wide pore‐size distributions, membrane fouling …

Downstream processing of cell culture-derived virus particles

MW Wolf, U Reichl - Expert Review of Vaccines, 2011 - Taylor & Francis
Manufacturing of cell culture-derived virus particles for vaccination and gene therapy is a
rapidly growing field in the biopharmaceutical industry. The process involves a number of …