Over the past year, numerous studies in the peer reviewed and preprint literature have
reported on the virological, epidemiological and clinical characteristics of the coronavirus …

Highlights•Variation in both HLA and SARS-CoV-2 impact antigen presentation to T
cells.•HLA variation influences COVID-19 outcomes and T-cell responses to SARS-CoV …

Abstract BNT162b2, a nucleoside-modified mRNA formulated in lipid nanoparticles that
encodes the SARS-CoV-2 spike glycoprotein (S) stabilized in its prefusion conformation, has …

T cells are important for effective viral clearance, elimination of virus-infected cells, and long-
term disease protection. To examine the full spectrum of CD8+ T cell immunity in COVID-19 …

CD8+ T cell immunity to SARS-CoV-2 has been implicated in COVID-19 severity and virus
control. Here, we identified nonsynonymous mutations in MHC-I-restricted CD8+ T cell …

BNT162b2, a lipid nanoparticle (LNP) formulated nucleoside-modified messenger RNA
(mRNA) encoding the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

T cell responses play an important role in protection against beta-coronavirus infections,
including SARS-CoV-2, where they associate with decreased COVID-19 disease severity …

T cell-mediated immunity plays an important role in controlling SARS-CoV-2 infection, but
the repertoire of naturally processed and presented viral epitopes on class I human …

The COVID-19 pandemic caused by SARS-CoV-2 is a continuous challenge worldwide, and
there is an urgent need to map the landscape of immunogenic and immunodominant …

Beginning in May 2022, a novel cluster of monkeypox virus infections was detected in
humans. This virus has spread rapidly to non-endemic countries, sparking global concern …