Pancreatic cancer is a lethal disease with limited opportunity for resectable surgery as the
first choice for cure due to its late diagnosis and early metastasis. The desmoplastic stroma …

Neuropilin 1 (NRP1) represents one of the two homologous neuropilins (NRP, splice
variants of neuropilin 2 are the other) found in all vertebrates. It forms a transmembrane …

Background Redirecting pre-existing virus-specific cytotoxic CD8+ T lymphocytes (CTLs) to
tumors by simulating a viral infection of the tumor cells has great potential for cancer …

Triple-negative breast cancer (TNBC) has long been considered a major clinical challenge
due to its aggressive behavior and poor prognosis. Cancer stem cells (CSCs) are known as …

Neuropilin-1 (NRP-1) is a multifunctional transmembrane receptor for ligands that affect
developmental axonal growth and angiogenesis. In addition to a role in cancer, NRP-1 is a …

The COVID-19 pandemic continues without specific treatment. In this study it is proposed
compounds that can be developed as adjuvant/complementary drugs against COVID-19 …

Chimeric antigen receptor-T (CAR-T) cells and antibody-drug conjugates (ADCs) are
promising therapeutic strategies in oncology. The carcinoembryonic antigen-related cell …

The aim of this study was to investigate the role of high mobility group protein-1 (HMGB1) in
the proliferation and migration of lung cancer cells. CCK-8 assays and colony formation …

Background With the advent of large-scale molecular profiling, an increasing number of
oncogenic drivers contributing to precise medicine and reshaping classification of lung …

Non‐small‐cell lung cancer (NSCLC) is one of the most devastating diseases worldwide.
The study is aimed at identifying reliable prognostic biomarkers and to improve …