Cells within cells: Rickettsiales and the obligate intracellular bacterial lifestyle
J Salje - Nature Reviews Microbiology, 2021 - nature.com
The Rickettsiales are a group of obligate intracellular vector-borne Gram-negative bacteria
that include many organisms of clinical and agricultural importance, including Anaplasma …
that include many organisms of clinical and agricultural importance, including Anaplasma …
Engineering of obligate intracellular bacteria: progress, challenges and paradigms
EE McClure, ASO Chávez, DK Shaw… - Nature Reviews …, 2017 - nature.com
It is estimated that approximately one billion people are at risk of infection with obligate
intracellular bacteria, but little is known about the underlying mechanisms that govern their …
intracellular bacteria, but little is known about the underlying mechanisms that govern their …
Recent advances in genetic systems in obligate intracellular human-pathogenic bacteria
DJ Fisher, PA Beare - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
The ability to genetically manipulate a pathogen is fundamental to discovering factors
governing host–pathogen interactions at the molecular level and is critical for devising …
governing host–pathogen interactions at the molecular level and is critical for devising …
Pathogenic Rickettsia spp. as emerging models for bacterial biology
B Sit, RL Lamason - Journal of Bacteriology, 2024 - Am Soc Microbiol
Our understanding of free-living bacterial models like Escherichia coli far outpaces that of
obligate intracellular bacteria, which cannot be cultured axenically. All obligate intracellular …
obligate intracellular bacteria, which cannot be cultured axenically. All obligate intracellular …
The neglected challenge: Vaccination against rickettsiae
A Osterloh - PLoS neglected tropical diseases, 2020 - journals.plos.org
Over the last decades, rickettsioses are emerging worldwide. These diseases are caused by
intracellular bacteria. Although rickettsioses can be treated with antibiotics, a vaccine …
intracellular bacteria. Although rickettsioses can be treated with antibiotics, a vaccine …
Development of inducible promoter and CRISPRi plasmids functional in Rickettsia rickettsii
AM Nock, TR Clark, T Hackstadt - Journal of Bacteriology, 2024 - journals.asm.org
Rickettsia rickettsii is an obligate intracellular, tick-borne bacterium that causes Rocky
Mountain spotted fever. The demanding nature of cultivating these bacteria within host cells …
Mountain spotted fever. The demanding nature of cultivating these bacteria within host cells …
Peptide Nucleic Acid Knockdown and Intra-host Cell Complementation of Ehrlichia Type IV Secretion System Effector
Survival of Ehrlichia chaffeensis depends on obligatory intracellular infection. One of the
barriers to E. chaffeensis research progress has been the inability, using conventional …
barriers to E. chaffeensis research progress has been the inability, using conventional …
Orientia tsutsugamushi: A life between escapes
L Fromm, J Mehl, C Keller - MicrobiologyOpen, 2023 - Wiley Online Library
To replicate within host cells, intracellular bacteria have evolved different strategies to
invade, replicate, persist in, and eventually exit from their hosts. The intracellular lifestyle …
invade, replicate, persist in, and eventually exit from their hosts. The intracellular lifestyle …
Examination of Rickettsial Host Range for Shuttle Vectors Based on dnaA and parA Genes from the pRM Plasmid of Rickettsia monacensis
The genus Rickettsia encompasses a diverse group of obligate intracellular bacteria that are
highly virulent disease agents of mankind as well as symbionts of arthropods. Native …
highly virulent disease agents of mankind as well as symbionts of arthropods. Native …
Transmission of Amblyomma maculatum-Associated Rickettsia spp. During Cofeeding on Cattle
JK Lee, JV Stokes, GM Moraru, AB Harper… - Vector-Borne and …, 2018 - liebertpub.com
Amblyomma maculatum is the primary vector for the spotted fever group rickettsiae,
Rickettsia parkeri, a known pathogen, and “Candidatus Rickettsia andeanae,” currently …
Rickettsia parkeri, a known pathogen, and “Candidatus Rickettsia andeanae,” currently …