Alzheimer's disease (AD) is a neurodegenerative disease, in which the primary etiology
remains unknown. AD presents amyloid beta (Aβ) protein aggregation and neurofibrillary …

The last decade brought tremendous progress in the field of schizophrenia genetics. As a
result of extensive collaborations and multiple technological advances, we now recognize …

The mammalian target of rapamycin (mTOR) is an ubiquitously expressed serine-threonine
kinase, which senses and integrates several intracellular and environmental cues to …

Schizophrenia-related psychosis is associated with disturbances in mesolimbic dopamine
(DA) transmission, characterized by hyperdopaminergic activity in the mesolimbic pathway …

Several genome-and proteome-wide studies have associated transcription and translation
changes of CRMP2 (collapsing response mediator protein 2) with psychiatric disorders, yet …

Growing clinical and pre-clinical evidence points to a critical role for cannabidiol (CBD), the
largest phytochemical component of cannabis, as a potential pharmacotherapy for various …

Collapsin response mediator proteins (CRMPs) are a family of ubiquitously expressed,
homologous phosphoproteins best known for coordinating cytoskeletal formation and …

Maternal autoantibody-related ASD (MAR ASD) is a subtype of autism in which pathogenic
maternal autoantibodies (IgG) cross the placenta, access the developing brain, and cause …

Neuronal polarity and spatial rearrangement of neuronal processes are central to the
development of all mature nervous systems. Recent studies have highlighted the dynamic …

As a major eukaryotic cell clearing machinery, autophagy grants cell proteostasis, which is
key for neurotransmitter release, synaptic plasticity, and neuronal survival. In line with this …