The cellular model for Alzheimer's disease research: PC12 cells

D Xie, T Deng, Z Zhai, T Sun, Y Xu - Frontiers in Molecular …, 2023 - frontiersin.org
Alzheimer's disease (AD) is a common age-related neurodegenerative disease
characterized by progressive cognitive decline and irreversible memory impairment …

[HTML][HTML] A critical appraisal on ferulic acid: Biological profile, biopharmaceutical challenges and nano formulations

ND Raj, D Singh - Health Sciences Review, 2022 - Elsevier
Abstract Ferulic acid (4-hydroxy-3-methoxy cinnamic acid) is a common phenolic acid in the
plant kingdom and an important component of Chinese medicine herbs like Angelica …

[HTML][HTML] Maximizing the relevance and reproducibility of A549 cell culture using FBS-free media

A Chary, K Groff, AO Stucki, S Contal, C Stoffels… - Toxicology in Vitro, 2022 - Elsevier
Scientists are using in vitro methods to answer important research questions and
implementing strategies to maximize the reliability and human relevance of these methods …

The potential of Ginkgo biloba in the treatment of human diseases and the relationship to Nrf2–mediated antioxidant protection

Y Li, X Zhu, K Wang, L Zhu, M Murray… - Journal of Pharmacy …, 2022 - academic.oup.com
Objectives This review summarises the current findings regarding the therapeutic effects of
GBE and its active ingredients in relation to the Nrf2 antioxidant cascade, to provide …

Effect of oligomers derived from biodegradable polyesters on eco-and neurotoxicity

N Yoshinaga, A Tateishi, Y Kobayashi, T Kubo… - …, 2023 - ACS Publications
Biodegradable polymers are eco-friendly materials and have attracted attention for use in a
sustainable society because they are not accumulated in the environment. Although the …

[HTML][HTML] Decellularized lotus petioles integrated microfluidic chips for neural cell alignment monitoring

N Xia, Y Zhu, R Liu, W Chen, Y Zhao, L Sun - Composites Part B …, 2023 - Elsevier
Proper alignment of neural cells is critical for maintaining their physiological function, while it
is still challenging to induce and monitor such alignment in a cost-effective manner. Here …

Synthesis and biological evaluation of 1, 2, 4-triazole derivatives as potential Nrf2 activators for the treatment of cerebral ischemic injury

Y Lao, Y Wang, J Chen, P Huang, R Su, J Shi… - European Journal of …, 2022 - Elsevier
Acute ischemic stroke is a leading cause of disability and death. The development of
neuroprotectants is an emerging strategy for the treatment of ischemic stroke. In this work …

Novel Approach to the Treatment of Neuropathic Pain Using a Combination with Palmitoylethanolamide and Equisetum arvense L. in an In Vitro Study

S Ruga, R Galla, S Ferrari, M Invernizzi… - International Journal of …, 2023 - mdpi.com
Neuropathic pain is a typical patient disorder resulting from damage and dysfunction of the
peripheral neuraxis. Injury to peripheral nerves in the upper extremities can result in a …

Comparative study of the protective and neurotrophic effects of neuronal and glial progenitor cells-derived conditioned media in a model of glutamate toxicity in vitro

G Leonov, D Salikhova, M Shedenkova, T Bukharova… - Biomolecules, 2023 - mdpi.com
Cell therapy represents a promising approach to the treatment of neurological diseases,
offering potential benefits not only by cell replacement but also through paracrine secretory …

The strategic uses of collagen in adherent cell cultures

PF Chua, WK Lim - Cell Biology International, 2023 - Wiley Online Library
The culture of adherent mammalian cells involves adhesion to the tissue culture vessel. This
requires attachment factors from serum and/or a suitable substrate on the vessel surface …