Alzheimer's disease (AD) is a progressive and fatal neurodegenerative disease, with no
effective treatment or cure. A gold standard therapy would be treatment to slow or halt …

Introduction: The apolipoprotein E ɛ4-allele (APOE-ɛ4) increases the risk not only for
Alzheimer's disease (AD) but also for Parkinson's disease dementia and dementia with …

Purpose and Objectives Neurologic deficits after brain radiation therapy (RT) typically
involve decline in higher-order cognitive functions such as attention and memory rather than …

The Alzheimer's Disease Neuroimaging (ADNI) database is an expansive undertaking by
government, academia, and industry to pool resources and data on subjects at various stage …

There is convincing evidence that abnormalities of regional brain function exist in
Parkinson's disease (PD). However, many resting-state functional magnetic resonance …

Background: Patients with amnestic mild cognitive impairment (aMCI) have an increased
risk of dementia. However, conversion rate varies. Therefore, predicting the dementia …

Background and purpose Incidental irradiation of normal brain tissue during radiotherapy is
linked to cognitive decline, and may be mediated by damage to healthy cortex. Non …

To characterize the course of Alzheimer's disease (AD) over a longer time interval, we aimed
to construct a disease course model for the entire span of the disease using two separate …

Objective: Previous studies have shown that the e4-allele of the APOE gene is associated
with a higher risk of developing dementia. Our study investigated whether well-known …

We evaluated how the impact of apolipoprotein E4 (APOE4) differs according to age in
Alzheimer's disease (AD) patients. We recruited 846 AD patients and 815 cognitively normal …