Histotripsy is a focused ultrasound therapy for non-invasive tissue ablation. Unlike thermally
ablative forms of therapeutic ultrasound, histotripsy relies on the mechanical action of …

The last two decades have seen the development of acoustically activated droplets, also
known as phase-change emulsions, from a diagnostic tool to a therapeutic agent. Through …

Multimodal molecular imaging has shown promise as a complementary approach to
thrombus detection. However, the simultaneous noninvasive detection and lysis of thrombi …

Nanodroplets–emerging phase-changing sonoresponsive materials–have attracted
substantial attention in biomedical applications for both tumour imaging and therapeutic …

The development of phase-shift droplets has broadened the scope of ultrasound-based
biomedical applications. When subjected to sufficient acoustic pressures, the …

We have successfully fabricated versatile folate-targeted and oxygen/indocyanine green-
loaded lipid nanoparticles (FA-OINPs) for dual-mode imaging-guided therapy in ovarian …

Photothermal therapy (PTT) utilizes photothermal conversion reagents to generate heat
energy from absorbed light to effectively treat various malignant diseases. This approach …

Acoustic droplet vaporization (ADV) is the physical process in which liquid undergoes phase
transition to gas after exposure to a pressure amplitude above a certain threshold. In recent …

Phase-change contrast agents are rapidly developing as an alternative to microbubbles for
ultrasound imaging and therapy. These agents are synthesized and delivered as liquid …

Vascularization is a critical step following implantation of an engineered tissue construct in
order to maintain its viability. The ability to spatially pattern or direct vascularization could be …