The development of novel synthetic strategies to form new chemical entities in a
stereoselective manner is an ongoing significant objective in organic and medicinal …

Spirocyclic pyrrolidines are structural motifs frequently found in a wide variety of natural
products, pharmaceuticals and biologically significant compounds. In the past few years …

Spiroindole and spirooxindole scaffolds are very important spiro-heterocyclic compounds in
drug design processes. Significant attention has been directed at obtaining molecules …

Chiral indole derivatives are an intriguing class of heterocyclic compounds; their structural
motifs are frequently found in natural products and synthetic compounds with significant …

Nitrogen-containing heterocyclic compounds are some of the most significant compounds
that are produced artificially or naturally. These heterocyclic rings are virtually always …

Catalytic asymmetric construction of the biologically important spiro [pyrrolidin‐3, 2′‐
oxindole] scaffold with contiguous quaternary stereogenic centers in excellent …

Azomethine ylides are nitrogen-based three-atom components commonly used in [3+ 2]-
cycloaddition reactions with various unsaturated 2π-electron components. These reactions …

The 1, 3-dipolar cycloaddition of azomethine ylides derived from substituted isatins and 1, 3-
thiazolane-4-carboxylic acid to a series of 2-(arylmethylene)-2, 3-dihydro-1H-inden-1-ones …

Spirooxindolo-pyrrolidine, pyrrolizine and pyrrolothiazole hybrid compounds were obtained
in excellent yields from the regio-and stereoselective reaction between β-nitrostyrenes and …

3-Spiro [cyclopropa [a] pyrrolizine]-and 3-spiro [3-azabicyclo [3.1. 0] hexane] oxindoles were
prepared in moderate to high yields via one-pot three-component reactions using …