Combination therapy with long-acting bronchodilators and the risk of major adverse cardiovascular events in patients with COPD: a systematic review and meta …

M Yang, Y Li, Y Jiang, S Guo, JQ He… - European Respiratory …, 2023 - Eur Respiratory Soc
Introduction Accumulated high-quality data from randomised controlled trials (RCTs)
indicate that long-acting muscarinic antagonist (LAMA)/long-acting β2 agonist (LABA) …

Digital health in chronic obstructive pulmonary disease

H Long, S Li, Y Chen - Chronic Diseases and Translational Medicine, 2023 - mednexus.org
Chronic obstructive pulmonary disease (COPD) can be prevented and treated through
effective care, reducing exacerbations and hospitalizations. Early identification of individuals …

[HTML][HTML] Clinical characteristics, treatment persistence, and outcomes among patients with COPD treated with single-or multiple-inhaler triple therapy: a retrospective …

B Alcázar-Navarrete, L Jamart, J Sánchez-Covisa… - Chest, 2022 - Elsevier
Background COPD is a leading cause of death and disability. COPD therapy goals include
reducing exacerbations and improving symptom control. Single-inhaler triple therapy (SITT) …

Beyond dual bronchodilation–triple therapy, when and why

M Cazzola, P Rogliani, R Laitano… - … Journal of Chronic …, 2022 - Taylor & Francis
Although pharmacological treatment of COPD is codified in different guidelines and strategy
documents, there is abundant evidence of discrepancy between what they suggest and what …

The impact of 52-week single inhaler device triple therapy versus dual therapy on the mortality of COPD patients: a systematic review and meta-analysis of …

CC Lai, CH Chen, KH Chen, CY Wang, TM Huang… - Life, 2022 - mdpi.com
There are more single inhaler device triple therapy available for COPD patients now.
However, the effect of long-term triple therapy fixed dose combination (FDC) on mortality …

A 7-point evidence-based care discharge protocol for patients hospitalized for exacerbation of COPD: consensus strategy and expert recommendation

S Salvi, D Ghorpade, S Nair, L Pinto… - npj Primary Care …, 2024 - nature.com
Acute exacerbations of COPD (ECOPD) are an important event in the life of a COPD patient
as it causes significant deterioration of physical, mental, and social health, hastens disease …

Clinical and economic outcomes in patients with chronic obstructive pulmonary disease initiating maintenance therapy with tiotropium bromide/olodaterol or …

S Sethi, SR Palli, LGS Bengtson, EK Buysman… - Journal of Managed …, 2023 - jmcp.org
BACKGROUND: Clinical practice guidelines recommend dual long-acting muscarinic
antagonists (LAMAs)/long-acting β2agonists (LABAs) as maintenance therapy in patients …

Comparative effectiveness and safety of triple therapy and non-triple therapy interventions for COPD: an overview of systematic reviews

S Zhang, J Wang, X Li, H Zhang - Therapeutic Advances in …, 2024 - journals.sagepub.com
Background: Some systematic reviews (SRs) on triple therapy (consisting of long-acting β2-
agonist, long-acting muscarinic antagonist, and inhaled corticosteroid, LABA/LAMA/ICS) for …

Effects of triple therapy on disease burden in patients of GOLD groups C and D: results from the observational COPD cohort COSYCONET

JA Zader, RA Jörres, I Mayer, P Alter, R Bals… - BMC Pulmonary …, 2024 - Springer
Background Randomized controlled trials described beneficial effects of inhaled triple
therapy (LABA/LAMA/ICS) in patients with chronic obstructive pulmonary disease (COPD) …

Cost-effectiveness of triple therapy with budesonide/glycopyrronium/formoterol fumarate dihydrate versus dual therapies in moderate-to-very severe chronic …

E De Nigris, C Treharne, N Brighton… - … Journal of Chronic …, 2022 - Taylor & Francis
Background In the 52-week ETHOS study (NCT02465567), fixed-dose triple therapy with
budesonide/glycopyrronium/formoterol fumarate dihydrate (BGF) reduced moderate or …