Novel patterns of response and progression to immunotherapy have been reported that are
not observed with conventional cytotoxic or targeted anticancer treatments. A major …

Immunotherapy (IO) has altered the therapeutic landscape for multiple cancers. There are
emerging data from retrospective studies on a subset of patients who do not benefit from IO …

Purpose Hyperprogression is an atypical response pattern to immune checkpoint inhibition
that has been described within non-small cell lung cancer (NSCLC). The paradoxical …

The aim of this retrospective study was to detail the main clinicopathological characteristics
of advanced cancer patients exhibiting hyperprogressive disease (HPD) during immune …

Hyperprogression and pseudoprogression are two atypical responses to immune
checkpoint inhibitor therapy that affect therapeutic decisions and prognosis. Identification of …

Non-small cell lung cancer tumors follow an orderly progression from adenocarcinoma in
situ (AIS) to minimally invasive carcinoma (MIA) and invasive adenocarcinoma (INV) …