Soft‐tissue sarcoma in adults: an update on the current state of histiotype‐specific management in an era of personalized medicine

AC Gamboa, A Gronchi… - CA: a cancer journal for …, 2020 - Wiley Online Library
Soft‐tissue sarcomas (STS) are rare tumors that account for 1% of all adult malignancies,
with over 100 different histologic subtypes occurring predominately in the trunk, extremity …

[HTML][HTML] The management of desmoid tumours: a joint global consensus-based guideline approach for adult and paediatric patients

B Alman, S Attia, C Baumgarten, C Benson… - European Journal of …, 2020 - Elsevier
Desmoid tumor (DT; other synonymously used terms: Desmoid-type fibromatosis,
aggressive fibromatosis) is a rare and locally aggressive monoclonal, fibroblastic …

Nirogacestat, a γ-secretase inhibitor for desmoid tumors

M Gounder, R Ratan, T Alcindor… - … England Journal of …, 2023 - Mass Medical Soc
Background Desmoid tumors are rare, locally aggressive, highly recurrent soft-tissue tumors
without approved treatments. Methods We conducted a phase 3, international, double-blind …

Soft tissue and visceral sarcomas: ESMO–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

PG Casali, N Abecassis, S Bauer, R Biagini… - Annals of …, 2018 - annalsofoncology.org
Soft tissue sarcomas (STSs) gather over 80 histological entities, with even more molecular
subsets, characterised by a low to very low incidence in all populations. The majority of …

[HTML][HTML] Sorafenib for advanced and refractory desmoid tumors

MM Gounder, MR Mahoney, BA Van Tine… - … England Journal of …, 2018 - Mass Medical Soc
Background Desmoid tumors (also referred to as aggressive fibromatosis) are connective
tissue neoplasms that can arise in any anatomical location and infiltrate the mesentery …

[HTML][HTML] Surgery in reference centers improves survival of sarcoma patients: a nationwide study

JY Blay, C Honore, E Stoeckle, P Meeus, M Jafari… - Annals of …, 2019 - Elsevier
Background NETSARC (netsarc. org) is a network of 26 sarcoma reference centers with
specialized multidisciplinary tumor boards (MDTB) aiming to improve the outcome of …

[PDF][PDF] Treatment of acute Achilles tendon rupture

D Utashima, N Matsumura, T Suzuki… - Clinics in …, 2020 - synapse.koreamed.org
Background Synovial chondromatosis occurs rarely in the shoulder, and its details remain
unclear. The purpose of this study was to clarify the clinical results of surgical resection and …

Hypertrophic scars and keloids: advances in treatment and review of established therapies

FS Frech, L Hernandez, R Urbonas, GA Zaken… - American journal of …, 2023 - Springer
Hypertrophic scars and keloids can have significant detrimental effects on patients both
psychosocially and functionally. A careful identification of patient risk factors and a …

Pazopanib or methotrexate–vinblastine combination chemotherapy in adult patients with progressive desmoid tumours (DESMOPAZ): a non-comparative, randomised …

M Toulmonde, M Pulido, I Ray-Coquard… - The Lancet …, 2019 - thelancet.com
Background Desmoid tumours are locally aggressive tumours associated with substantial
morbidity. No systemic treatments are approved for this disease, with methotrexate …

Desmoid tumors: a comprehensive review

M Bektas, T Bell, S Khan, B Tumminello… - Advances in …, 2023 - Springer
Desmoid tumors (DT) are rare, locally aggressive, fibroblastic soft-tissue tumors that are
characterized by infiltrative growth and can affect organs and adjacent structures, resulting …