Background Breast cancer is the most common female cancer in Africa. Receptor-defined
subtypes are a major determinant of treatment options and disease outcomes but there is …

The presence of extracellular circulating or cell-free RNA in biological fluids is becoming a
promising diagnostic tool for non invasive and cost effective cancer detection. Extracellular …

Tumor markers play an important role in the early diagnosis and therapeutic effect
monitoring of tumors. Combined detection of multiple tumor markers is a realistic way of …

Background MicroRNA-34a (miR-34a) is a master regulator of tumor suppression in breast
cancer (BC). This systematic review aims to analyze the diagnostic accuracy of miR-34a in …

Early detection of cancer is vital to improved overall survival rates. At present, evidence is
accumulating for the clinical value of detecting occult tumor cells in peripheral blood …

Introduction: It is now clear that circulating cell-free ribonucleic acids (ccfRNAs), including
messenger RNA (mRNA) and miRNA, are potential cancer biomarkers. As ccfmiRNA is …

The incidence of atrial fibrillation (AF) increases with age, and telomere length gradually
shortens with age. However, whether telomere length is related to AF is still inconclusive …

Aims To investigate the diagnostic, predictive, and prognostic value of the detection of
circulating tumor cells (CTCs) using a three-marker (CK19, hMAM and CEA) RT-PCR assay …

Background Cytokeratin 19 fragment antigen (CYFRA 21–1) is used to diagnose and
monitor neoplasms. However, the main disadvantages of the currently available CYFRA 21 …

To compare the value of cytokeratin fragment 21-1 (CYFRA 21-1) concentration in the fine-
needle biopsy aspirates (fine needle aspirate [FNA] CYFRA 21-1) with cytopathology of fine …