Click chemistry: 1, 2, 3‐triazoles as pharmacophores
SG Agalave, SR Maujan… - Chemistry–An Asian …, 2011 - Wiley Online Library
Abstract The copper (I)‐catalyzed 1, 2, 3‐triazole‐forming reaction between azides and
terminal alkynes has become the gold standard of 'click chemistry'due to its reliability …
terminal alkynes has become the gold standard of 'click chemistry'due to its reliability …
Recent researches in triazole compounds as medicinal drugs
CH Zhou, Y Wang - Current medicinal chemistry, 2012 - ingentaconnect.com
Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole
ring are readily able to bind with a variety of enzymes and receptors in biological system via …
ring are readily able to bind with a variety of enzymes and receptors in biological system via …
Acylhydrazones and their biological activity: a review
LI Socea, SF Barbuceanu, EM Pahontu, AC Dumitru… - Molecules, 2022 - mdpi.com
Due to the structure of acylhydrazones both by the pharmacophore–CO–NH–N= group and
by the different substituents present in the molecules of compounds of this class, various …
by the different substituents present in the molecules of compounds of this class, various …
Recent developments on 1, 2, 4-triazole nucleus in anticancer compounds: a review
R Kaur, A Ranjan Dwivedi, B Kumar… - Anti-Cancer Agents in …, 2016 - ingentaconnect.com
1, 2, 4-triazole is an important nucleus present in a large number of compounds. More than
thirty-five compounds containing this nucleus are introduced into the market. 1, 2, 4-triazole …
thirty-five compounds containing this nucleus are introduced into the market. 1, 2, 4-triazole …
Bioactive 1, 2, 3‐Triazoles: An Account on their Synthesis, Structural Diversity and Biological Applications
L da SM Forezi, CGS Lima, AAP Amaral… - The Chemical …, 2021 - Wiley Online Library
The triazole heterocycle is a privileged scaffold in medicinal chemistry, since its structure is
present in a large number of biologically active molecules, including several drugs currently …
present in a large number of biologically active molecules, including several drugs currently …
Silica mesoporous structures: effective nanocarriers in drug delivery and nanocatalysts
M Mirzaei, MB Zarch, M Darroudi, K Sayyadi… - Applied Sciences, 2020 - mdpi.com
The application of silica mesoporous structures in drug delivery and the removal of
pollutants and organic compounds through catalytic reactions is increasing due to their …
pollutants and organic compounds through catalytic reactions is increasing due to their …
Direct access to 1, 2, 3-triazoles through organocatalytic 1, 3-dipolar cycloaddition reaction of allyl ketones with azides
W Li, Z Du, J Huang, Q Jia, K Zhang, J Wang - Green Chemistry, 2014 - pubs.rsc.org
Direct access to 1,2,3-triazoles through organocatalytic 1,3-dipolar cycloaddition reaction of
allyl ketones with azides - Green Chemistry (RSC Publishing) DOI:10.1039/C4GC00406J …
allyl ketones with azides - Green Chemistry (RSC Publishing) DOI:10.1039/C4GC00406J …
[HTML][HTML] Synthesis and anti-HSV-1 activity of new 1, 2, 3-triazole derivatives
AK Jordão, VF Ferreira, TML Souza… - Bioorganic & medicinal …, 2011 - Elsevier
In this work, a new series of arysulfonylhydrazine-1H-1, 2, 3-triazole derivatives were
synthesized, and their ability to inhibit the in vitro replication of HSV-1 was evaluated …
synthesized, and their ability to inhibit the in vitro replication of HSV-1 was evaluated …
Hetero-Diels-Alder reactions of novel 3-triazolyl-nitrosoalkenes as an approach to functionalized 1, 2, 3-triazoles with antibacterial profile
The generation and reactivity of 3-triazolyl-nitrosoalkenes are reported for the first time. The
study showed that hetero-Diels-Alder reaction of these heterodienes is an interesting …
study showed that hetero-Diels-Alder reaction of these heterodienes is an interesting …
Efficient synthesis of diverse 5-thio-or 5-selenotriazoles: One-pot multicomponent reaction from elemental sulfur or selenium
LL Zhang, YT Li, T Gao, SS Guo, B Yang, ZH Meng… - …, 2019 - thieme-connect.com
A sequential multistep reaction toward 5-thio-or 5-selenotriazoles has been established by
generation of both copper (I) triazolides and sulfenylating or selenylating agents in situ …
generation of both copper (I) triazolides and sulfenylating or selenylating agents in situ …