Unexplained post-acute infection syndromes
SARS-CoV-2 is not unique in its ability to cause post-acute sequelae; certain acute
infections have long been associated with an unexplained chronic disability in a minority of …
infections have long been associated with an unexplained chronic disability in a minority of …
[HTML][HTML] COVID-19, post-acute COVID-19 syndrome (PACS,“long COVID”) and post-COVID-19 vaccination syndrome (PCVS,“post-COVIDvac-syndrome”): Similarities …
F Scholkmann, CA May - Pathology-Research and Practice, 2023 - Elsevier
Worldwide there have been over 760 million confirmed coronavirus disease 2019 (COVID-
19) cases, and over 13 billion COVID-19 vaccine doses have been administered as of April …
19) cases, and over 13 billion COVID-19 vaccine doses have been administered as of April …
Recent progress in Lyme disease and remaining challenges
Lyme disease (also known as Lyme borreliosis) is the most common vector-borne disease in
the United States with an estimated 476,000 cases per year. While historically, the long-term …
the United States with an estimated 476,000 cases per year. While historically, the long-term …
[HTML][HTML] Post-treatment Lyme disease as a model for persistent symptoms in Lyme disease
It has long been observed in clinical practice that a subset of patients with Lyme disease
report a constellation of symptoms such as fatigue, cognitive difficulties, and musculoskeletal …
report a constellation of symptoms such as fatigue, cognitive difficulties, and musculoskeletal …
A selective antibiotic for Lyme disease
Lyme disease is on the rise. Caused by a spirochete Borreliella burgdorferi, it affects an
estimated 500,000 people in the United States alone. The antibiotics currently used to treat …
estimated 500,000 people in the United States alone. The antibiotics currently used to treat …
Determinants of persistent symptoms after treatment for Lyme borreliosis: a prospective observational cohort study
HD Vrijmoeth, J Ursinus, MG Harms, AD Tulen… - …, 2023 - thelancet.com
Summary Background Patients treated for Lyme borreliosis (LB) frequently report persistent
symptoms. Little is known about risk factors and etiology. Methods In a prospective …
symptoms. Little is known about risk factors and etiology. Methods In a prospective …
[HTML][HTML] Risk of post-treatment Lyme disease in patients with ideally-treated early Lyme disease: A prospective cohort study.
JN Aucott, T Yang, I Yoon, D Powell, SA Geller… - International Journal of …, 2022 - Elsevier
Abstract Purpose Post-treatment Lyme disease (PTLD) is characterized by patient-reported
symptoms after treatment for Borrelia burgdorferi infection. The primary aim of this study was …
symptoms after treatment for Borrelia burgdorferi infection. The primary aim of this study was …
Imaging glial activation in patients with post-treatment Lyme disease symptoms: a pilot study using [11C]DPA-713 PET
The pathophysiology of post-treatment Lyme disease syndrome (PTLDS) may be linked to
overactive immunity including aberrant activity of the brain's resident immune cells …
overactive immunity including aberrant activity of the brain's resident immune cells …
Systematic comparisons between Lyme disease and post-treatment Lyme disease syndrome in the US with administrative claims data
Summary Background Post-treatment Lyme disease syndrome (PTLDS) is used to describe
Lyme disease patients who have the infection cleared by antibiotic but then experienced …
Lyme disease patients who have the infection cleared by antibiotic but then experienced …
Estimation of cumulative number of post-treatment Lyme disease cases in the US, 2016 and 2020
A DeLong, M Hsu, H Kotsoris - BMC Public Health, 2019 - Springer
Background Lyme disease (LD) is an infectious multi-system illness caused by the bacterial
genus Borrelia and spread by bites of infected ticks. Although most patients are successfully …
genus Borrelia and spread by bites of infected ticks. Although most patients are successfully …