Background Although great achievements have been made in the field of cancer therapy,
chemotherapy and radiotherapy remain the mainstay cancer therapeutic modalities …

Cisplatin is a potent platinum-based anticancer drug approved by the Food Drug
Administration (FDA) in 1978. Despite its advantages against solid tumors, cisplatin confers …

Background Liver is a vital organ responsible for metabolizing and detoxifying both
endogenous and exogenous substances in the body. However, it is susceptible to damage …

The liver is not only involved in metabolism and detoxification, but also participate in innate
immune function and thus exposed to frequent target Thus, they are the frequent target of …

In this work, water-resistant poly (vinyl alcohol)(PVA)/poly (acrylic acid)(PAA) electrospun
fibers encapsulating tangeretin (Tan) were fabricated by emulsion-electrospinning. To …

Natural compounds with pharmacological activity, flavonoids have been the subject of an
exponential increase in studies in the field of scientific research focused on therapeutic …

Chlorpyrifos (CPF) is an agricultural pesticide and a potential food contaminant, which
causes neurotoxicity. Here, we aimed at exploring the link between the repeated exposure …

Background Liver diseases and related complications are major sources of morbidity and
mortality, which places a huge financial burden on patients and lead to nonnegligible social …

Cisplatin is one of the most potent anti-cancer drugs used for the treatment of various solid
tumors, yet it has several side effects that may limit its clinical use. Hepatotoxicity is one of …

Cisplatin is one of the most widely used chemotherapeutic anti-cancer drugs that is
associated with multiple systemic toxicities limiting its use. The present study aimed to …