Immunological properties of oxygen-transport proteins: hemoglobin, hemocyanin and hemerythrin

CJ Coates, H Decker - Cellular and Molecular Life Sciences, 2017 - Springer
It is now well documented that peptides with enhanced or alternative functionality (termed
cryptides) can be liberated from larger, and sometimes inactive, proteins. A primary example …

THB 1, a truncated hemoglobin, modulates nitric oxide levels and nitrate reductase activity

E Sanz‐Luque, F Ocaña‐Calahorro… - The Plant …, 2015 - Wiley Online Library
Hemoglobins are ubiquitous proteins that sense, store and transport oxygen, but the
physiological processes in which they are implicated is currently expanding. Recent …

Sphaerotilus natans hemoglobins have an NADH oxidation activity and promote the yield of limonene in an engineered E. coli strain

M Li, Z Yang, S Chen, Z Liu, L Tong, S Zheng… - International Journal of …, 2024 - Elsevier
Bacterial hemoglobins play important roles inside the cell. Phylogenetically, they belong to
three different families: the single domain hemoglobin, flavohemoglobin and truncated …

Roles of N-and C-terminal domains in the ligand-binding properties of cytoglobin

S Hanai, H Tsujino, T Yamashita, R Torii… - Journal of Inorganic …, 2018 - Elsevier
Cytoglobin (Cygb) is a member of the hexacoordinated globin protein family and is
expressed ubiquitously in rat and human tissues. Although Cygb is reportedly upregulated …

New Insights Into the Function of Flavohemoglobin in Mycobacterium tuberculosis: Role as a NADPH-Dependent Disulfide Reductase and D-Lactate-Dependent …

N Thakur, AN Sharma, MD Hade, A Chhaya… - Frontiers in Cellular …, 2022 - frontiersin.org
Mycobacterium tuberculosis (Mtb) produces an unconventional flavohemoglobin (Mtb FHb)
that carries a FAD-binding site similar to D-lactate dehydrogenases (D-LDH) and oxidizes D …

Molecular Model of Hemoglobin N from Mycobacterium tuberculosis Bound to Lipid Bilayers: A Combined Spectroscopic and Computational Study

JF Rhéault, È Gagné, M Guertin, G Lamoureux… - Biochemistry, 2015 - ACS Publications
A singular aspect of the 2-on-2 hemoglobin structures of groups I and II is the presence of
tunnels linking the protein surface to the distal heme pocket, supporting the storage and the …

Mechanism of the Nitric Oxide Dioxygenase Reaction of Mycobacterium tuberculosis Hemoglobin N

LA Carabet, M Guertin, P Lague… - The Journal of Physical …, 2017 - ACS Publications
Many globins convert• NO to innocuous NO3–through their nitric oxide dioxygenase (NOD)
activity. Mycobacterium tuberculosis fights the oxidative and nitrosative stress imposed by its …

THB1 regulates nitrate reductase activity and THB1 and THB2 transcription differentially respond to NO and the nitrate/ammonium balance in Chlamydomonas

E Sanz-Luque, F Ocaña-Calahorro… - Plant signaling & …, 2015 - Taylor & Francis
Nitric oxide (NO) has emerged as an important regulator of the nitrogen assimilation
pathway in plants. Nevertheless, this free radical is a double-edged sword for cells due to its …

Multidomain truncated hemoglobins: new members of the globin family exhibiting tandem repeats of globin units and domain fusion

MD Hade, J Kaur, PK Chakraborti, KL Dikshit - IUBMB life, 2017 - Wiley Online Library
Truncated hemoglobins (trHbs) are considered the most primitive members of globin
superfamily and traditionally exist as a single domain heme protein in three distinct structural …

Direct Monitoring of the Reaction between Photochemically Generated Nitric Oxide and Mycobacterium tuberculosis Truncated Hemoglobin N Wild Type and Variant …

KJ Koebke, MT Waletzko, AA Pacheco - Biochemistry, 2016 - ACS Publications
The previously reported nitric oxide precursor [Mn (PaPy2Q) NO] ClO4 (1), where
(PaPy2QH) is N, N-bis (2-pyridylmethyl)-amine-N-ethyl-2-quinoline-2-carboxamide, was …