ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries
This review summarizes the last decade of work by the ENIGMA (E nhancing N euro I
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …
[HTML][HTML] Image harmonization: A review of statistical and deep learning methods for removing batch effects and evaluation metrics for effective harmonization
Magnetic resonance imaging and computed tomography from multiple batches (eg sites,
scanners, datasets, etc.) are increasingly used alongside complex downstream analyses to …
scanners, datasets, etc.) are increasingly used alongside complex downstream analyses to …
Heart-brain connections: Phenotypic and genetic insights from magnetic resonance images
Cardiovascular health interacts with cognitive and mental health in complex ways, yet little is
known about the phenotypic and genetic links of heart-brain systems. We quantified heart …
known about the phenotypic and genetic links of heart-brain systems. We quantified heart …
Disparities in the pace of biological aging among midlife adults of the same chronological age have implications for future frailty risk and policy
Some humans age faster than others. Variation in biological aging can be measured in
midlife, but the implications of this variation are poorly understood. We tested associations …
midlife, but the implications of this variation are poorly understood. We tested associations …
[HTML][HTML] Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank
UK Biobank is a large-scale prospective epidemiological study with all data accessible to
researchers worldwide. It is currently in the process of bringing back 100,000 of the original …
researchers worldwide. It is currently in the process of bringing back 100,000 of the original …
Harmonization of multi-site diffusion tensor imaging data
Diffusion tensor imaging (DTI) is a well-established magnetic resonance imaging (MRI)
technique used for studying microstructural changes in the white matter. As with many other …
technique used for studying microstructural changes in the white matter. As with many other …
Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group
The regional distribution of white matter (WM) abnormalities in schizophrenia remains poorly
understood, and reported disease effects on the brain vary widely between studies. In an …
understood, and reported disease effects on the brain vary widely between studies. In an …
White matter disturbances in major depressive disorder: a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group
Alterations in white matter (WM) microstructure have been implicated in the pathophysiology
of major depressive disorder (MDD). However, previous findings have been inconsistent …
of major depressive disorder (MDD). However, previous findings have been inconsistent …
The development of brain white matter microstructure
Throughout infancy, childhood, and adolescence, our brains undergo remarkable changes.
Processes including myelination and synaptogenesis occur rapidly across the first 2–3 years …
Processes including myelination and synaptogenesis occur rapidly across the first 2–3 years …
Abnormal asymmetries in subcortical brain volume in schizophrenia
N Okada, M Fukunaga, F Yamashita… - Molecular …, 2016 - nature.com
Subcortical structures, which include the basal ganglia and parts of the limbic system, have
key roles in learning, motor control and emotion, but also contribute to higher-order …
key roles in learning, motor control and emotion, but also contribute to higher-order …