Microphthalmia-associated transcription factor (MITF) is an important regulator of
melanogenesis and melanocyte development. Although it has been studied extensively in …

Molecular biology studies of uveal melanoma have resulted in the development of novel
immunotherapy approaches including tebentafusp—a T cell–redirecting bispecific fusion …

The visual appearance of humans is derived significantly from our skin and hair color. While
melanin from epidermal melanocytes protects our skin from the damaging effects of …

It was recently demonstrated that newly invented positronium imaging may be used for
improving cancer diagnostics by providing additional information about tissue pathology …

Simple Summary The prognosis of uveal melanoma is dependent on many factors. Among
the most relevant are the tumour size, ciliary body involvement, extraocular extension …

It remains unclear how the multifunctional indoleamine neurohormone, melatonin, alters
melanin production and melanocytes within intact human epidermis under physiologically …

Background G protein-coupled receptors (GPCRs) have been shown to have an important
role in tumor development and metastasis, and abnormal expression of GPCRs is …

The skin–brain axis has been suggested to play a role in several pathophysiological
conditions, including opioid addiction, Parkinson's disease and many others. Recent …

Simple Summary The tumor environment is the place where the tumor resides implying that
it might evolve in the role of disease progression, particularly in the phase of tumor …

Simple Summary Melanoma is a type of skin cancer that often spreads and is a significant
cause of skin-tumor-related deaths. Checkpoint inhibition with anti-programmed death …