A systematic review and meta-analysis of the diagnostic accuracy of prostate health index and 4-kallikrein panel score in predicting overall and high-grade prostate …

GI Russo, F Regis, T Castelli, V Favilla… - Clinical genitourinary …, 2017 - Elsevier
Markers for prostate cancer (PCa) have progressed over recent years. In particular, the
prostate health index (PHI) and the 4-kallikrein (4K) panel have been demonstrated to …

[HTML][HTML] Blood and urine biomarkers in prostate cancer: Are we ready for reflex testing in men with an elevated prostate-specific antigen?

EK Chang, AJ Gadzinski, YA Nyame - Asian Journal of Urology, 2021 - Elsevier
Objective There is no consensus on the role of biomarkers in determining the utility of
prostate biopsy in men with elevated prostate-specific antigen (PSA). There are numerous …

A multicentre evaluation of the role of the prostate health index (PHI) in regions with differing prevalence of prostate cancer: adjustment of PHI reference ranges is …

PKF Chiu, CF Ng, A Semjonow, Y Zhu, S Vincendeau… - European urology, 2019 - Elsevier
Asians have a lower incidence of prostate cancer (PC). We compared the performance of
the Prostate Health Index (PHI) for 2488 men in different ethnic groups (1688 Asian and 800 …

Enhancement of prostate cancer diagnosis by machine learning techniques: an algorithm development and validation study

PKF Chiu, X Shen, G Wang, CL Ho, CH Leung… - Prostate cancer and …, 2022 - nature.com
Background To investigate the value of machine learning (ML) in enhancing prostate cancer
(PCa) diagnosis. Methods Consecutive systematic prostate biopsies performed from Jan …

[HTML][HTML] Molecular biomarkers for the detection of clinically significant prostate cancer: a systematic review and meta-analysis

T Del Pino-Sedeno, D Infante-Ventura… - European Urology Open …, 2022 - Elsevier
Abstract Context Prostate cancer (PCa) is the second most common type of cancer in men.
Individualized risk stratification is crucial to adjust decision-making. A variety of molecular …

[HTML][HTML] Usefulness of the prostate health index in predicting the presence and aggressiveness of prostate cancer among Korean men: a prospective observational …

JY Kim, JH Yu, LH Sung, DY Cho, HJ Kim, SJ Yoo - BMC urology, 2021 - Springer
Background We aimed to evaluate the usefulness of the Beckman Coulter prostate health
index (PHI) and to compare it with total prostate-specific antigen (PSA) levels and related …

Personalized strategies in population screening for prostate cancer

S Remmers, MJ Roobol - International Journal of Cancer, 2020 - Wiley Online Library
This review discusses evidence for population‐based screening with contemporary
screening tools. In Europe, prostate‐specific antigen (PSA)‐based screening led to a …

[HTML][HTML] Early diagnosis of prostate cancer from the perspective of Chinese physicians

W Yu, L Zhou - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Prostate cancer (PCa) is the seventh most diagnosed cancer and the tenth leading cause of
cancer mortality in China. Unlike the USA, both incidence and mortality continue to increase …

[HTML][HTML] The combined role of MRI prostate and prostate health index in improving detection of significant prostate cancer in a screening population of Chinese men

PKF Chiu, TYT Lam, CF Ng, JYC Teoh… - Asian Journal of …, 2023 - journals.lww.com
Using prostate-specific antigen (PSA) for prostate cancer (PCa) screening led to
overinvestigation and overdiagnosis of indolent PCa. We aimed to investigate the value of …

Initial Prostate Health Index (phi) and phi density predicts future risk of clinically significant prostate cancer in men with initial negative prostate biopsy: a 6-year follow …

AQ Liu, S Remmers, SY Lau, SY Yip… - Prostate Cancer and …, 2022 - nature.com
Background Men with elevated prostate-specific antigen (PSA) and initial negative prostate
biopsy may have risk of prostate cancer (PCa) in the future. The role of Prostate Health Index …