[HTML][HTML] Signaling pathways and therapeutic interventions in gastric cancer

ZN Lei, QX Teng, Q Tian, W Chen, Y Xie… - Signal transduction and …, 2022 - nature.com
Gastric cancer (GC) ranks fifth in global cancer diagnosis and fourth in cancer-related death.
Despite tremendous progress in diagnosis and therapeutic strategies and significant …

Glioblastoma: current status, emerging targets, and recent advances

A Thakur, C Faujdar, R Sharma, S Sharma… - Journal of Medicinal …, 2022 - ACS Publications
Glioblastoma (GBM) is a highly malignant brain tumor characterized by a heterogeneous
population of genetically unstable and highly infiltrative cells that are resistant to …

Nanoparticle-based drug delivery systems in cancer: A focus on inflammatory pathways

AR Afshari, M Sanati, H Mollazadeh… - Seminars in cancer …, 2022 - Elsevier
It has become necessary to accept the clinical reality of therapeutic agents targeting the
cancer-associated immune system. In recent decades, several investigations have …

Recent trends in the application of nanoparticles in cancer therapy: The involvement of oxidative stress

M Sanati, AR Afshari, P Kesharwani… - Journal of Controlled …, 2022 - Elsevier
In the biomedical area, the interdisciplinary field of nanotechnology has the potential to bring
numerous unique applications, including better tactics for cancer detection, diagnosis, and …

[HTML][HTML] NF-κB inhibitors gifted by nature: The anticancer promise of polyphenol compounds

C Guan, X Zhou, H Li, X Ma, J Zhuang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Polyphenol compounds are natural antioxidants, which are rich in anti-inflammatory and
antioxidant components. They have a wide range of medicinal benefits that are believed to …

Effects of statins on brain tumors: a review

AR Afshari, H Mollazadeh, NC Henney… - Seminars in Cancer …, 2021 - Elsevier
Evidence from preclinical studies suggests that the competitive HMG-CoA reductase
(HMGCR) inhibitors universally known as' statins,'in addition to being powerful drugs that …

[HTML][HTML] Differentially expressed miRNAs in ulcerative colitis and Crohn's disease

R Yarani, A Shojaeian, O Palasca… - Frontiers in …, 2022 - frontiersin.org
Differential microRNA (miRNA or miR) regulation is linked to the development and progress
of many diseases, including inflammatory bowel disease (IBD). It is well-established that …

Advantages and drawbacks of dexamethasone in glioblastoma multiforme

AR Afshari, M Sanati, S Aminyavari, F Shakeri… - Critical Reviews in …, 2022 - Elsevier
The most widespread, malignant, and deadliest type of glial tumor is glioblastoma
multiforme (GBM). Despite radiation, chemotherapy, and radical surgery, the median …

[HTML][HTML] In silico and in vitro screening of 50 curcumin compounds as EGFR and NF-κB inhibitors

MEM Saeed, R Yücer, M Dawood, MEF Hegazy… - International Journal of …, 2022 - mdpi.com
The improvement of cancer chemotherapy remains a major challenge, and thus new drugs
are urgently required to develop new treatment regimes. Curcumin, a polyphenolic …

Treatment of oxidative stress, apoptosis, and DNA injury with N-acetylcysteine at simulative pesticide toxicity in fish

M Atamanalp, V Parlak, FB Özgeriş… - Toxicology …, 2021 - Taylor & Francis
Pesticide toxicities are common in aquatic ecosystems and affects aquatic livings negative.
Therefore, it is important to strengthen the antioxidant system in aquatic organisms and to …