Superoxide dismutases Page 66 SUPEROXIDE DISMUTASES By IRWIN FRIDOVICH,
Department of Biochemistry, Duke University Medical Center, Durham, North Carolina …

It is generally accepted that the principal roles of metallothionein lie in the detoxification of
heavy metals and regulation of the metabolism of essential trace metals. However, there is …

An increased production of oxygen radicals has been postulated to be a major factor in the
etiology of lung damage during hyperoxia. Mitochondrial electron transport was inhibited …

Copper-and zinc-containing superoxide dismutase, manganese-containing superoxide
dismutase, catalase, and glutathione peroxidase form the primary enzymic defense against …

ALTHOUGH THE free radical hypothesis of aging is often ascribed to articles published by
Gerschman et al.(1954) and by Harman in the 1950s, the idea, as currently perceived, has a …

Tumor necrosis factor (TNF) induces the synthesis of protein (s) that can protect cells against
subsequent killing by TNF in the presence of cycloheximide. Here we demonstrate that …

A considerable amount of evidence now makes it clear that aerobic tissues require an
elaborate enzyme system to remove the harmful reaction products of oxygen reduction. A …

The activity of superoxide dismutases (SOD) I and 2 was analysed in correlation with mRNA
and chromosome content in 6 SV40‐transformed (TF) and in non‐transformed (NF) human …

These volumes of Copper Proteins and Copper Enzymes are intended to describe the
contemporary spectroscopy and other biophysical chemistry now being applied to copper …

Interleukin 1 (IL 1) inhibits the growth of human melanoma A375 cells (1). To identify the
subcellular events preceding inhibition of growth by IL 1, we have examined the effect of IL 1 …