Functional properties of insect olfactory receptors: ionotropic receptors and odorant receptors

D Wicher, F Miazzi - Cell and Tissue Research, 2021 - Springer
The majority of insect olfactory receptors belong to two distinct protein families, the
ionotropic receptors (IRs), which are related to the ionotropic glutamate receptor family, and …

Drosophila chemoreceptors: a molecular interface between the chemical world and the brain

RM Joseph, JR Carlson - Trends in Genetics, 2015 - cell.com
Chemoreception is essential for survival. Feeding, mating, and avoidance of predators
depend on detection of sensory cues. Drosophila contains diverse families of …

Sensing odorants and pheromones with chemosensory receptors

K Touhara, LB Vosshall - Annual review of physiology, 2009 - annualreviews.org
Olfaction is a critical sensory modality that allows living things to acquire chemical
information from the external world. The olfactory system processes two major classes of …

Insect olfaction from model systems to disease control

AF Carey, JR Carlson - Proceedings of the National …, 2011 - National Acad Sciences
Great progress has been made in the field of insect olfaction in recent years. Receptors,
neurons, and circuits have been defined in considerable detail, and the mechanisms by …

Drosophila odorant receptors are novel seven transmembrane domain proteins that can signal independently of heterotrimeric G proteins

R Smart, A Kiely, M Beale, E Vargas, C Carraher… - Insect biochemistry and …, 2008 - Elsevier
Olfaction in Drosophila is mediated by a large family of membrane-bound odorant receptor
proteins (Ors). In heterologous cells, we investigated whether the structural features and …

Single-cell transcriptomes of developing and adult olfactory receptor neurons in Drosophila

CN McLaughlin, M Brbić, Q Xie, T Li, F Horns… - Elife, 2021 - elifesciences.org
Recognition of environmental cues is essential for the survival of all organisms.
Transcriptional changes occur to enable the generation and function of the neural circuits …

Blood meal-induced changes to antennal transcriptome profiles reveal shifts in odor sensitivities in Anopheles gambiae

DC Rinker, RJ Pitts, X Zhou, E Suh… - Proceedings of the …, 2013 - National Acad Sciences
Olfactory-driven behaviors are central to the lifecycle of the malaria vector mosquito
Anopheles gambiae and are initiated by peripheral signaling in the antenna and other …

The role of the coreceptor Orco in insect olfactory transduction

M Stengl, NW Funk - Journal of Comparative Physiology A, 2013 - Springer
Insects sense odorants with specialized odorant receptors (ORs). Each antennal olfactory
receptor neuron expresses one OR with an odorant binding site together with a conserved …

Amino acid residues contributing to function of the heteromeric insect olfactory receptor complex

T Nakagawa, M Pellegrino, K Sato, LB Vosshall… - PloS one, 2012 - journals.plos.org
Olfactory receptors (Ors) convert chemical signals—the binding of odors and pheromones—
to electrical signals through the depolarization of olfactory sensory neurons. Vertebrates Ors …

Mimicking nature's noses: From receptor deorphaning to olfactory biosensing

R Glatz, K Bailey-Hill - Progress in neurobiology, 2011 - Elsevier
The way in which organisms detect specific volatile compounds within their environment,
and the associated neural processing which produces perception and subsequent …