Retinal development and maturation are orchestrated by a series of interacting signalling
networks that drive the morphogenetic transformation of the anterior developing brain …

Inherited retinal diseases (IRDs) cause progressive loss of light-sensitive photoreceptors in
the eye and can lead to blindness. Gene-based therapies for IRDs have shown remarkable …

Biological computing (or biocomputing) offers potential advantages over silicon-based
computing in terms of faster decision-making, continuous learning during tasks, and greater …

High-definition vision in humans and nonhuman primates is initiated by cone photoreceptors
located within a specialized region of the retina called the fovea. Foveal cone death is the …

The development of the visual system involves the coordination of spatial and temporal
events to specify the organization of varied cell types, including the elongation of axons from …

Humans rely on visual cues to navigate the world around them. Vision begins with the
detection of light by photoreceptor cells in the retina, a light-sensitive tissue located at the …

Human pluripotent stem cell (hPSC)-derived retinal organoids (ROs) can efficiently and
reproducibly generate retinal neurons that have potential for use in cell replacement …

Recent advances have driven the development of stem cell-derived, self-organizing, three-
dimensional miniature organs, termed organoids, which mimic different eye tissues …

Despite being the most prevalent cause of inherited blindness in children, Stargardt disease
is yet to achieve the same clinical trial success as has been achieved for other inherited …

Gene expression provides valuable insight into cell function. As such, vision researchers
have frequently employed gene expression studies to better understand retinal physiology …