Clinical metagenomics—challenges and future prospects

M Batool, J Galloway-Peña - Frontiers in Microbiology, 2023 - frontiersin.org
Infections lacking precise diagnosis are often caused by a rare or uncharacterized
pathogen, a combination of pathogens, or a known pathogen carrying undocumented or …

The underrated gut microbiota helminths, bacteriophages, fungi, and archaea

MJ Garcia-Bonete, A Rajan, F Suriano, E Layunta - Life, 2023 - mdpi.com
The microbiota inhabits the gastrointestinal tract, providing essential capacities to the host.
The microbiota is a crucial factor in intestinal health and regulates intestinal physiology …

Ad interim recommendations for diagnosing SARS-CoV-2 infection by the IFCC SARS-CoV-2 variants working group

G Lippi, J Favresse, MM Gromiha… - Clinical Chemistry and …, 2022 - degruyter.com
This document, endorsed by the IFCC Working Group on SARS-CoV-2 Variants, aims to
update previous indications for diagnosing acute SARS-CoV-2 infection, taking into …

[HTML][HTML] Significance of wastewater surveillance in detecting the prevalence of SARS-CoV-2 variants and other respiratory viruses in the community–a multi-site …

M Khan, L Li, L Haak, SH Payen, M Carine, K Adhikari… - One Health, 2023 - Elsevier
Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral genome
in wastewater has proven to be useful for tracking the trends of virus prevalence within the …

Novel receptor, mutation, vaccine, and establishment of coping mode for SARS-CoV-2: current status and future

Z Zeng, X Geng, X Wen, Y Chen, Y Zhu… - Frontiers in …, 2023 - frontiersin.org
Since the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and
its resultant pneumonia in December 2019, the cumulative number of infected people …

Application of next-generation sequencing to identify different pathogens

AM Nafea, Y Wang, D Wang, AM Salama… - Frontiers in …, 2024 - frontiersin.org
Early and precise detection and identification of various pathogens are essential for
epidemiological monitoring, disease management, and reducing the prevalence of clinical …

Bioinformatic tools for NGS-based metagenomics to improve the clinical diagnosis of emerging, re-emerging and new viruses

M Ibañez-Lligoña, S Colomer-Castell… - Viruses, 2023 - mdpi.com
Epidemics and pandemics have occurred since the beginning of time, resulting in millions of
deaths. Many such disease outbreaks are caused by viruses. Some viruses, particularly …

Micro-and nanosystems for the detection of hemorrhagic fever viruses

M Bao, J Waitkus, L Liu, Y Chang, Z Xu, P Qin, J Chen… - Lab on a Chip, 2023 - pubs.rsc.org
Hemorrhagic fever viruses (HFVs) are virulent pathogens that can cause severe and often
fatal illnesses in humans. Timely and accurate detection of HFVs is critical for effective …

Aptamer‐Based Strategies to Address Challenges in COVID‐19 Diagnosis and Treatments

ZY Chang, FAMS Alhamami… - … Perspectives on Infectious …, 2023 - Wiley Online Library
Coronavirus disease (COVID‐19), a highly contagious and rapidly spreading disease with
significant fatality in the elderly population, has swept across the world since 2019. Since its …

Impact of nanopore-based metagenome sequencing on tick-borne virus detection

K Ergunay, E Dincer, SA Justi, BP Bourke… - Frontiers in …, 2023 - frontiersin.org
Introduction We evaluated metagenomic nanopore sequencing (NS) in field-collected ticks
and compared findings from amplification-based assays. Methods Forty tick pools collected …