Ancient DNA analysis

L Orlando, R Allaby, P Skoglund… - Nature reviews …, 2021 - nature.com
Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …

The Genomics of Cannabis and Its Close Relatives

I Kovalchuk, M Pellino, P Rigault… - Annual Review of …, 2020 - annualreviews.org
Cannabis sativa L. is an important yet controversial plant with a long history of recreational,
medicinal, industrial, and agricultural use, and together with its sister genus Humulus, it …

Large-scale whole-genome resequencing unravels the domestication history of Cannabis sativa

G Ren, X Zhang, Y Li, K Ridout… - Science …, 2021 - science.org
Cannabis sativa has long been an important source of fiber extracted from hemp and both
medicinal and recreational drugs based on cannabinoid compounds. Here, we investigated …

Recent advances in cannabis biotechnology

M Hesami, M Pepe, M Alizadeh, A Rakei… - Industrial Crops and …, 2020 - Elsevier
Cannabis sativa L. is a high-value crop with a multi-billion dollar international market, yet
due to the long history of prohibition, there is a significant lack of research on the plant and …

A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination

K Miettinen, N Leelahakorn, A Almeida, Y Zhao… - Nature …, 2022 - nature.com
Eukaryotic cells use G-protein coupled receptors to sense diverse signals, ranging from
chemical compounds to light. Here, we exploit the remarkable sensing capacity of G-protein …

Cannabis sativa: origin and history, glandular trichome development, and cannabinoid biosynthesis

Z Xie, Y Mi, L Kong, M Gao, S Chen… - Horticulture …, 2023 - academic.oup.com
Is Cannabis a boon or bane? Cannabis sativa has long been a versatile crop for fiber
extraction (industrial hemp), traditional Chinese medicine (hemp seeds), and recreational …

Cannabis‐related allergies: An international overview and consensus recommendations

IJ Skypala, S Jeimy, H Brucker, AP Nayak, II Decuyper… - Allergy, 2022 - Wiley Online Library
Cannabis is the most widely used recreational drug in the world. Cannabis sativa and
Cannabis indica have been selectively bred to develop their psychoactive properties. The …

Understanding Cannabis sativa L.: Current Status of Propagation, Use, Legalization, and Haploid-Inducer-Mediated Genetic Engineering

DC Simiyu, JH Jang, OR Lee - Plants, 2022 - mdpi.com
Cannabis sativa L. is an illegal plant in many countries. The worldwide criminalization of the
plant has for many years limited its research. Consequently, understanding the full scope of …

Ancient roots of today's emerging renaissance in psychedelic medicine

DR George, R Hanson, D Wilkinson… - Culture, Medicine, and …, 2022 - Springer
An international ban on psychedelics initiated by the United Nations' Convention on
Psychotropic Substances in 1971 restricted the clinical use of these ancient psychoactive …

A balanced approach for cannabidiol use in chronic pain

DA Argueta, CM Ventura, S Kiven, V Sagi… - Frontiers in …, 2020 - frontiersin.org
Cannabidiol (CBD), the major non-psychoactive constituent of Cannabis sativa L., has
gained traction as a potential treatment for intractable chronic pain in many conditions …