Recent advances in deep learning for protein-protein interaction analysis: A comprehensive review

M Lee - Molecules, 2023 - mdpi.com
Deep learning, a potent branch of artificial intelligence, is steadily leaving its transformative
imprint across multiple disciplines. Within computational biology, it is expediting progress in …

Cellenboost: a boosting-based ligand-receptor interaction identification model for cell-to-cell communication inference

L Peng, R Yuan, C Han, G Han, J Tan… - IEEE Transactions …, 2023 - ieeexplore.ieee.org
Cell-to-cell communication (CCC) plays important roles in multicellular organisms. The
identification of communication between cancer cells themselves and one between cancer …

MaTPIP: A deep-learning architecture with eXplainable AI for sequence-driven, feature mixed protein-protein interaction prediction

S Ghosh, P Mitra - Computer Methods and Programs in Biomedicine, 2024 - Elsevier
Abstract Background and Objective Protein-protein interaction (PPI) is a vital process in all
living cells, controlling essential cell functions such as cell cycle regulation, signal …

Knowledge mapping of graph neural networks for drug discovery: a bibliometric and visualized analysis

R Yao, Z Shen, X Xu, G Ling, R Xiang, T Song… - Frontiers in …, 2024 - frontiersin.org
Introduction In recent years, graph neural network has been extensively applied to drug
discovery research. Although researchers have made significant progress in this field, there …

Response score-based protein structure analysis for cancer prediction aided by the Internet of Things

O Alruwaili, A Yousef, TA Jumani, A Armghan - Scientific Reports, 2024 - nature.com
Medical diagnosis through prediction and analysis is par excellence in integrating modern
technologies such as the Internet of Things (IoT). With the aid of such technologies, clinical …

Variable importance in high-dimensional settings requires grouping

A Chamma, B Thirion, D Engemann - Proceedings of the AAAI …, 2024 - ojs.aaai.org
Explaining the decision process of machine learning algorithms is nowadays crucial for both
model's performance enhancement and human comprehension. This can be achieved by …

Exploring the alignment landscape: Llms and geometric deep models in protein representation

D Shu, B Duan, K Guo, K Zhou, J Tang… - arXiv preprint arXiv …, 2024 - arxiv.org
Latent representation alignment has become a foundational technique for constructing
multimodal large language models (MLLM) by mapping embeddings from different …

MVSF-AB: Accurate antibody-antigen binding affinity prediction via multi-view sequence feature learning

M Li, Y Shi, S Hu, S Hu, P Guo, W Wan, LY Zhang… - …, 2024 - academic.oup.com
Motivation Predicting the binding affinity between antigens and antibodies accurately is
crucial for assessing therapeutic antibody effectiveness and enhancing antibody …

Learning protein language contrastive models with multi-knowledge representation

W Xu, Y Xia, B Sun, Z Zhao, L Tang, X Zhou… - Future Generation …, 2025 - Elsevier
Protein representation learning plays a crucial role in obtaining a comprehensive
understanding of biological regulatory mechanisms and in developing proteins and drugs …

An Ensemble Classifiers for Improved Prediction of Native–Non-Native Protein–Protein Interaction

NKC Pratiwi, H Tayara, KT Chong - International Journal of Molecular …, 2024 - mdpi.com
In this study, we present an innovative approach to improve the prediction of protein–protein
interactions (PPIs) through the utilization of an ensemble classifier, specifically focusing on …