Carotenoids: biochemistry, pharmacology and treatment

A Milani, M Basirnejad, S Shahbazi… - British journal of …, 2017 - Wiley Online Library
Carotenoids and retinoids have several similar biological activities such as antioxidant
properties, the inhibition of malignant tumour growth and the induction of apoptosis …

Curcumin: A natural modulator of immune cells in systemic lupus erythematosus

AA Momtazi-Borojeni, SM Haftcheshmeh… - Autoimmunity …, 2018 - Elsevier
Curcumin is a polyphenol natural product isolated from turmeric, interacting with different
cellular and molecular targets and, consequently, showing a wide range of pharmacological …

Local administration of curcumin-loaded nanoparticles effectively inhibits inflammation and bone resorption associated with experimental periodontal disease

LMG Zambrano, DA Brandao, FRG Rocha… - Scientific reports, 2018 - nature.com
There is evidence indicating that curcumin has multiple biological activities, including anti-
inflammatory properties. In vitro and in vivo studies demonstrate that curcumin may …

Targeting the balance of T helper cell responses by curcumin in inflammatory and autoimmune states

K Rahimi, A Ahmadi, K Hassanzadeh, Z Soleimani… - Autoimmunity …, 2019 - Elsevier
Abstract CD4+ T helper (Th) cells are a crucial player in host defense but under certain
conditions can contribute to the pathogenesis of inflammatory and autoimmune diseases …

[HTML][HTML] Promising role of curcumin against viral diseases emphasizing COVID-19 management: A review on the mechanistic insights with reference to host-pathogen …

S Dhar, P Bhattacharjee - Journal of Functional Foods, 2021 - Elsevier
Curcumin has already acknowledged immense interest from both medical and scientific
research because of its multifaceted activity. To date, the promising effects of curcumin were …

Curcumin converts Foxp3+ regulatory T cells to T helper 1 cells in patients with lung cancer

JY Zou, CH Su, HH Luo, YY Lei, B Zeng… - Journal of Cellular …, 2018 - Wiley Online Library
The regulatory T cells (Treg) play an important role in the tumor tolerance. The methods to
regulate the Treg population in cancer‐bearing hosts are limited currently. The effect of …

Curcumin prevents osteoarthritis by inhibiting the activation of inflammasome NLRP3

Y Sun, W Liu, H Zhang, H Li, J Liu, F Zhang… - Journal of Interferon & …, 2017 - liebertpub.com
Curcumin has shown protective potential on osteoarthritis. However, its effect on treatment of
osteoarthritis remains elusive so far. This study aimed to determine whether curcumin could …

Curcumin mediates attenuation of pro-inflammatory interferon γ and interleukin 17 cytokine responses in psoriatic disease, strengthening its role as a dietary …

DΝ Skyvalidas, A Mavropoulos, S Tsiogkas… - Nutrition Research, 2020 - Elsevier
Curcumin exhibits anti-inflammatory properties and has been used for centuries in
traditional medicine and as dietary supplement. Data from clinical trials has strengthened …

Curcumin and endothelial function: evidence and mechanisms of protective effects

MS Karimian, M Pirro, TP Johnston… - Current …, 2017 - ingentaconnect.com
Background: The endothelium is a large paracrine organ regulating cell growth, vascular
tone and thrombogenicity as well as platelet and leukocyte interactions. Endothelial function …

Immunomodulatory effects of curcumin in rheumatoid arthritis: evidence from molecular mechanisms to clinical outcomes

S Mohammadian Haftcheshmeh, A Khosrojerdi… - Reviews of physiology …, 2021 - Springer
Rheumatoid arthritis (RA) is a chronic immune-mediated inflammatory disorder
characterized by the destruction of the joint and bone resorption. The production of pro …