Alzheimer's disease as a synaptopathy: Evidence for dysfunction of synapses during disease progression

S Meftah, J Gan - Frontiers in Synaptic Neuroscience, 2023 - frontiersin.org
The synapse has consistently been considered a vulnerable and critical target within
Alzheimer's disease, and synapse loss is, to date, one of the main biological correlates of …

[HTML][HTML] The impact of gamma transcranial alternating current stimulation (tACS) on cognitive and memory processes in patients with mild cognitive impairment or …

NR Nissim, DVH Pham, T Poddar, E Blutt, RH Hamilton - Brain stimulation, 2023 - Elsevier
Background Transcranial alternating current stimulation (tACS)—a noninvasive brain
stimulation technique that modulates cortical oscillations through entrainment—has been …

[HTML][HTML] An update on the use of gamma (multi) sensory stimulation for Alzheimer's disease treatment

V Manippa, A Palmisano, M Filardi, D Vilella… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is characterized by reduced fast brain oscillations in the gamma
band (γ,> 30 Hz). Several animal studies show that inducing gamma oscillations through …

Audiovisual gamma stimulation for the treatment of neurodegeneration

C Blanco‐Duque, D Chan, MC Kahn… - Journal of Internal …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is the most common type of neurodegenerative disease and a
health challenge with major social and economic consequences. In this review, we discuss …

Episodic memory effects of gamma frequency precuneus transcranial magnetic stimulation in Alzheimer's disease: A randomized multiple baseline study

A Traikapi, I Kalli, A Kyriakou… - Journal of …, 2023 - Wiley Online Library
Episodic memory decline is the prominent neuropsychological feature of typical Alzheimer's
Disease (AD), for which current treatments have a limited clinical response. Recently …

Home-based transcranial alternating current stimulation (tACS) in Alzheimer's disease: rationale and study design

D Altomare, A Benussi, V Cantoni, E Premi… - Alzheimer's Research & …, 2023 - Springer
Background Gamma (γ) brain oscillations are dysregulated in Alzheimer's disease (AD) and
can be modulated using transcranial alternating stimulation (tACS). In the present paper, we …

The role of aberrant neural oscillations in the hippocampal-medial prefrontal cortex circuit in neurodevelopmental and neurological disorders

N Shing, MC Walker, P Chang - Neurobiology of Learning and Memory, 2022 - Elsevier
The hippocampus (HPC) and medial prefrontal cortex (mPFC) have well-established roles in
cognition, emotion, and sensory processing. In recent years, interests have shifted towards …

Alzheimer's disease: A review on the current trends of the effective diagnosis and therapeutics

AS Abdul Manap, R Almadodi, S Sultana… - Frontiers in Aging …, 2024 - frontiersin.org
The most prevalent cause of dementia is Alzheimer's disease. Cognitive decline and
accelerating memory loss characterize it. Alzheimer's disease advances sequentially …

Transcranial alternating current stimulation combined with sound stimulation improves cognitive function in patients with Alzheimer's disease: study protocol for a …

Y Liu, S Liu, C Tang, K Tang, D Liu, M Chen… - Frontiers in Aging …, 2023 - frontiersin.org
Background The number of patients with Alzheimer's disease (AD) worldwide is increasing
yearly, but the existing treatment methods have poor efficacy. Transcranial alternating …

Transcranial magneto-acoustic stimulation improves spatial memory and modulates hippocampal neural oscillations in a mouse model of Alzheimer's disease

S Zhang, Z Guo, Y Xu, J Mi, J Liu, Z Li, X Xie… - Frontiers in …, 2024 - frontiersin.org
Introduction In our study, we applied transcranial magneto-acoustic stimulation (TMAS), a
technique based on focused ultrasound stimulation within a static magnetic field, in the …