Treatment and prevention of brain metastases in small cell lung cancer

R Rittberg, S Banerji, JO Kim, S Rathod… - American journal of …, 2021 - journals.lww.com
Central nervous system (CNS) metastasis will develop in 50% of small cell lung cancer
(SCLC) patients throughout disease course. Development of CNS metastasis poses a …

Prophylactic cranial irradiation in small cell lung cancer: a systematic review and meta-analysis

X Yin, D Yan, M Qiu, L Huang, SX Yan - Bmc Cancer, 2019 - Springer
Background The efficacy of prophylactic cranial irradiation (PCI) in treating patients with
small cell lung cancer (SCLC) has not been clear, and recent randomized studies have …

Small cell lung cancer, version 2.2022, NCCN clinical practice guidelines in oncology

AKP Ganti, BW Loo, M Bassetti, C Blakely… - Journal of the National …, 2021 - jnccn.org
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Small Cell Lung
Cancer (SCLC) provide recommended management for patients with SCLC, including …

Radiation therapy for small cell lung cancer: an ASTRO clinical practice guideline

CB Simone II, JA Bogart, AR Cabrera, ME Daly… - Practical radiation …, 2020 - Elsevier
Purpose Several sentinel phase III randomized trials have recently been published
challenging traditional radiation therapy (RT) practices for small cell lung cancer (SCLC) …

Radiotherapy for extensive-stage small-cell lung cancer in the immunotherapy era

H Li, Y Zhao, T Ma, H Shao, T Wang, S Jin… - Frontiers in …, 2023 - frontiersin.org
Currently, chemoimmunotherapy is the first-line treatment for extensive-stage small-cell lung
cancer (ES-SCLC). However, only 0.8%–2.5% of the patients presented complete response …

Prophylactic cranial irradiation effect on survival in patients with small cell lung cancer: a comprehensive systematic review and meta-analysis

SF Maroufi, MS Fallahi, SB Kankam, JP Sheehan - Neurosurgical Focus, 2023 - thejns.org
OBJECTIVE Prophylactic cranial irradiation (PCI) is a companion treatment option for small
cell lung cancer (SCLC) patients. However, its efficacy and associated risk factors have not …

Machine learning-based prediction model for brain metastasis in patients with extensive-stage small cell lung cancer

E Munai, S Zeng, Z Yuan, D Yang, Y Jiang, Q Wang… - Scientific Reports, 2024 - nature.com
Brain metastases (BMs) in extensive-stage small cell lung cancer (ES-SCLC) are often
associated with poor survival rates and quality of life, making the timely identification of high …

[HTML][HTML] Factors influencing the utilization of prophylactic cranial irradiation in patients with limited-stage small cell lung cancer

BH Lok, J Ma, A Foster, CA Perez, W Shi… - Advances in Radiation …, 2017 - Elsevier
Purpose Brain metastases are common in patients with limited-stage small cell lung cancer
(LS-SCLC) due to the inability of most chemotherapeutics to penetrate the blood–brain …

Optimizing lung cancer radiation treatment worldwide in COVID-19 outbreak

Z Liao, ER Del Campo, A Salem, Q Pang, H Liu… - Lung Cancer, 2020 - Elsevier
COVID-19 has spread around the planet, sending billions of people into lockdown as health
services struggle to cope. Meanwhile in Asia, where the disease began, the spread …

Patterns of failure in limited-stage small cell lung cancer: Implications of TNM stage for prophylactic cranial irradiation

AJ Wu, A Gillis, A Foster, K Woo, Z Zhang… - Radiotherapy and …, 2017 - Elsevier
Background and purpose The relationship between tumor-node-metastasis (TNM) stage
and patterns of failure in limited-stage small cell lung cancer (LS-SCLC) remains unclear …