Pharmacology and biochemistry of spider venoms

LD Rash, WC Hodgson - Toxicon, 2002 - Elsevier
Spider venoms represent an incredible source of biologically active substances which
selectively target a variety of vital physiological functions in both insects and mammals …

Brown spiders and loxoscelism

PH Da Silva, RB Da Silveira, MH Appel, OC Mangili… - Toxicon, 2004 - Elsevier
Accidents caused by brown spiders (Loxosceles genus) are classically associated with
dermonecrotic lesions and systemic manifestations including intravascular haemolysis …

Molecular diversity of spider venom

AA Vassilevski, SA Kozlov, EV Grishin - Biochemistry (Moscow), 2009 - Springer
Spider venom, a factor that has played a decisive role in the evolution of one of the most
successful groups of living organisms, is reviewed. Unique molecular diversity of venom …

Loxoscelism

DL Swanson, RS Vetter - Clinics in dermatology, 2006 - Elsevier
Loxoscelism (bites by spiders of the genus Loxosceles) is the only proven arachnological
cause of dermonecrosis. Although Loxosceles spiders can be found worldwide, their …

Recent advances in the understanding of brown spider venoms: From the biology of spiders to the molecular mechanisms of toxins

LH Gremski, D Trevisan-Silva, VP Ferrer… - Toxicon, 2014 - Elsevier
The Loxosceles genus spiders (the brown spiders) are encountered in all the continents,
and the clinical manifestations following spider bites include skin necrosis with gravitational …

Venom composition and strategies in spiders: is everything possible?

L Kuhn-Nentwig, R Stöcklin, W Nentwig - Advances in insect physiology, 2011 - Elsevier
This review on all spider venom components known by the end of 2010 bases on 1618
records for venom compounds from 174 spider species (= 0.41% of all known species) …

Cloning of a salivary gland metalloprotease and characterization of gelatinase and fibrin (ogen) lytic activities in the saliva of the Lyme disease tick vector Ixodes …

IMB Francischetti, TN Mather, JMC Ribeiro - Biochemical and biophysical …, 2003 - Elsevier
The full-length sequence of tick salivary gland cDNA coding for a protein similar to
metalloproteases (MP) of the reprolysin family is reported. The Ixodes scapularis MP is a …

Freshwater stingrays: study of epidemiologic, clinic and therapeutic aspects based on 84 envenomings in humans and some enzymatic activities of the venom

V Haddad Jr, DG Neto, JB de Paula Neto… - Toxicon, 2004 - Elsevier
Freshwater stingrays are very common in the Paraná, Paraguay, Araguaia, and Tocantins
Rivers and tributaries in Brazil. This study presents the clinical aspects of 84 patients injured …

Biotechnological trends in spider and scorpion antivenom development

AH Laustsen, M Solà, EC Jappe, S Oscoz… - Toxins, 2016 - mdpi.com
Spiders and scorpions are notorious for their fearful dispositions and their ability to inject
venom into prey and predators, causing symptoms such as necrosis, paralysis, and …

Brown spider dermonecrotic toxin directly induces nephrotoxicity

OM Chaim, YB Sade, RB da Silveira, L Toma… - Toxicology and applied …, 2006 - Elsevier
Brown spider (Loxosceles genus) venom can induce dermonecrotic lesions at the bite site
and systemic manifestations including fever, vomiting, convulsions, disseminated …