Mast cells (MCs) are best-known as key effector cells of immediate-type allergic reactions
that may even culminate in life-threatening anaphylactic shock syndromes. However …

The lymphatic vasculature has a pivotal role in regulating body fluid homeostasis, immune
surveillance and dietary fat absorption. The increasing number of in vitro and in vivo studies …

Ovarian cancer (OVCA) is the second most common gynecological cancer and one of the
leading causes of cancer related mortality among women. Recent studies suggest that …

Human lung mast cells (HLMCs) express the high-affinity receptor FcεRI for IgE and are
strategically located in different compartments of human lung, where they play a role in …

Although mast cells (MCs) are known as key drivers of type I allergic reactions, there is
increasing evidence for their critical role in host defense. MCs not only play an important role …

Secondary lymphedema of the extremities affects millions of people in the world as a
common side effect of oncological treatments with heavy impact on every day life of patients …

Background Accumulated evidence for systemic inflammation response in several solid
tumors prompts a possibility of prediction of patients' prognosis in a more accessible and …

Mast cells (MCs) are infamous for their role in potentially fatal anaphylaxis reactions. In the
last two decades, a more complex picture has emerged, as it has become obvious that MCs …

The bladder is a major component of the urinary tract, an organ system that expels metabolic
waste and excess water, which necessitates proximity to the external environment and its …

Background Lymphatic dysfunction exists in tumor necrosis factor transgenic (TNF-Tg) mice
and rheumatoid arthritis (RA) patients. While joint-draining TNF-Tg popliteal lymphatic …